Malaria parasite liver infection and exoerythrocytic biology
AM Vaughan, SHI Kappe - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
In their infection cycle, malaria parasites undergo replication and population expansions
within the vertebrate host and the mosquito vector. Host infection initiates with sporozoite …
within the vertebrate host and the mosquito vector. Host infection initiates with sporozoite …
Plasmodium Egress Across the Parasite Life Cycle
JD Dvorin, DE Goldberg - Annual review of microbiology, 2022 - annualreviews.org
Human malaria, caused by infection with Plasmodium parasites, remains one of the most
important global public health problems, with the World Health Organization reporting more …
important global public health problems, with the World Health Organization reporting more …
The Malaria Cell Atlas: Single parasite transcriptomes across the complete Plasmodium life cycle
INTRODUCTION Plasmodium parasites, the causative agent of malaria, are single-celled
organisms with distinct morphological developmental stages each specialized to inhabit …
organisms with distinct morphological developmental stages each specialized to inhabit …
Conditional expression of PfAP2-G for controlled massive sexual conversion in Plasmodium falciparum
O Llorà-Batlle, L Michel-Todó, K Witmer, H Toda… - Science …, 2020 - science.org
Malaria transmission requires that some asexual parasites convert into sexual forms termed
gametocytes. The initial stages of sexual development, including sexually committed …
gametocytes. The initial stages of sexual development, including sexually committed …
A toolbox to study liver stage malaria
The first obligatory phase of mammalian infection by Plasmodium parasites, the causative
agents of malaria, occurs in the liver of the host. This stage of Plasmodium infection bears …
agents of malaria, occurs in the liver of the host. This stage of Plasmodium infection bears …
A Plasmodium Phospholipase Is Involved in Disruption of the Liver Stage Parasitophorous Vacuole Membrane
The coordinated exit of intracellular pathogens from host cells is a process critical to the
success and spread of an infection. While phospholipases have been shown to play …
success and spread of an infection. While phospholipases have been shown to play …
Same, same but different: Exploring Plasmodium cell division during liver stage development
M Roques, A Bindschedler, R Beyeler… - PLoS …, 2023 - journals.plos.org
Plasmodium parasites have a complex life cycle alternating between a mosquito and a
vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium …
vertebrate host. Following the bite of an Anopheles female mosquito, Plasmodium …
Pre-erythrocytic malaria vaccines: identifying the targets
Pre-erythrocytic malaria vaccines target Plasmodium during its sporozoite and liver stages,
and can prevent progression to blood-stage disease, which causes a million deaths each …
and can prevent progression to blood-stage disease, which causes a million deaths each …
Hostile Takeover by Plasmodium: Reorganization of Parasite and Host Cell Membranes during Liver Stage Egress
S Graewe, KE Rankin, C Lehmann… - PLoS …, 2011 - journals.plos.org
The protozoan parasite Plasmodium is transmitted by female Anopheles mosquitoes and
undergoes obligatory development within a parasitophorous vacuole in hepatocytes before …
undergoes obligatory development within a parasitophorous vacuole in hepatocytes before …
Prison break: pathogens' strategies to egress from host cells
N Friedrich, M Hagedorn, D Soldati-Favre… - … and Molecular Biology …, 2012 - Am Soc Microbiol
SUMMARY A wide spectrum of pathogenic bacteria and protozoa has adapted to an
intracellular life-style, which presents several advantages, including accessibility to host cell …
intracellular life-style, which presents several advantages, including accessibility to host cell …