Genetic risk factors for osteochondrosis in various horse breeds

F Naccache, J Metzger, O Distl - Equine Veterinary Journal, 2018 - Wiley Online Library
Osteochondrosis (OC) is an injury to cartilage canals with a following necrosis in the growth
cartilage, from there it can develop to osteochondrosis dissecans (OCD). Due to its high …

Osteochondritis dissecans (OCD) in horses–Molecular background of its pathogenesis and perspectives for progenitor stem cell therapy

L Bourebaba, M Röcken, K Marycz - Stem cell reviews and reports, 2019 - Springer
Osteochondrosis (osteochondrosis dissecans; OCD) is a disease syndrome of growing
cartilage related to different clinical entities such as epiphysitis, subchondral cysts and …

Causal associations of circulating lipids with osteoarthritis: a bidirectional mendelian randomization study

H Meng, L Jiang, Z Song, F Wang - Nutrients, 2022 - mdpi.com
Osteoarthritis (OA) imposes an increasing social burden due to global activity limitations,
especially among the aged. Links between circulating lipids and OA have been reported; …

Platelets' functional peculiarities in persons of the second mature age with spinal column osteochondrosis of the second degree

AA Bikbulatova, EG Andreeva… - Annual Research & …, 2017 - archive.article4submit.com
Introduction: Many disturbances in a body are often accompanied by some disturbance of
blood parameters. Regular blood elements and, especially, platelets can play a significant …

Characterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training

BA McGivney, PA McGettigan, JA Browne, ACO Evans… - BMC genomics, 2010 - Springer
Background Digital gene expression profiling was used to characterize the assembly of
genes expressed in equine skeletal muscle and to identify the subset of genes that were …

Maternal obesity increases insulin resistance, low-grade inflammation and osteochondrosis lesions in foals and yearlings until 18 months of age

M Robles, E Nouveau, C Gautier, L Mendoza… - PLoS …, 2018 - journals.plos.org
Introduction Obesity is a growing concern in horses. The effects of maternal obesity on
maternal metabolism and low-grade inflammation during pregnancy, as well as offspring …

Association of breeding conditions with prevalence of osteochondrosis in foals

L Vander Heyden, JP Lejeune, I Caudron… - Veterinary …, 2013 - Wiley Online Library
Osteochondrosis (OC) is the most common developmental orthopaedic disease in horses
and represents a major problem to the horse industry. The complete mechanism of this …

The next generation: using new sequencing technologies to analyse gene regulation

R Cullum, O Alder, PA Hoodless - Respirology, 2011 - Wiley Online Library
Next generation sequencing (NGS) has pushed back the limitations of prior sequencing
technologies to advance genomic knowledge infinitely by allowing cost‐effective, rapid …

Gambling on putative biomarkers of osteoarthritis and osteochondrosis by equine synovial fluid proteomics

E Chiaradia, M Pepe, M Tartaglia, F Scoppetta… - Journal of …, 2012 - Elsevier
Osteoarthritis (OA) and osteochondrosis (OC) are two of the main challenges in orthopedics,
whose definitive diagnosis is usually based on radiographic/arthroscopic evidences. Their …

Genetics of equine orthopedic disease

J Metzger, O Distl - Veterinary Clinics: Equine Practice, 2020 - vetequine.theclinics.com
Orthopedic diseases in the horse constitute an important group of defects, particularly
including developmental and degenerative joint diseases, tendon and ligament defects, and …