The structural biochemistry of the superoxide dismutases

JJP Perry, DS Shin, ED Getzoff, JA Tainer - Biochimica et Biophysica Acta …, 2010 - Elsevier
The discovery of superoxide dismutases (SODs), which convert superoxide radicals to
molecular oxygen and hydrogen peroxide, has been termed the most important discovery of …

The basic and applied aspects of superoxide dismutase

A Bafana, S Dutt, A Kumar, S Kumar… - Journal of Molecular …, 2011 - Elsevier
Superoxide dismutase (SOD) is among the most potent antioxidants known in nature and is
an important constituent of cellular defence against oxidative stress. The enzyme shows …

Engineering a thermo-stable superoxide dismutase functional at sub-zero to> 50 C, which also tolerates autoclaving

A Kumar, S Dutt, G Bagler, PS Ahuja, S Kumar - Scientific reports, 2012 - nature.com
Superoxide dismutase (SOD) is a critical enzyme associated with controlling oxygen toxicity
arising out of oxidative stress in any living system. A hyper-thermostable SOD isolated from …

Superoxide dismutase: an industrial perspective

A Bafana, S Dutt, S Kumar, PS Ahuja - Critical reviews in …, 2011 - Taylor & Francis
The application of enzyme technologies to industrial research, development, and
manufacturing has become a very important field. Since the production of crude rennet in …

Inhibition of copper-zinc superoxide dismutase activity by selected environmental xenobiotics

Ł Lewandowski, M Kepinska, H Milnerowicz - … toxicology and pharmacology, 2018 - Elsevier
Abstract The function of Cu, Zn-SOD is to dismutate superoxide into hydrogen peroxide and
oxygen. This task is fulfilled due to structural nuances of the enzyme. Many environmental …

Role of superoxide dismutases (SODs) in stress tolerance in plants

S Tyagi, Shumayla, SP Singh, SK Upadhyay - Molecular approaches in …, 2019 - Springer
The plants get exposed to different abiotic stresses and pathogen attack due to their sessile
nature. These stresses result in the overproduction of reactive oxygen species (ROS) such …

Cytotoxicity of perfluorodecanoic acid on mouse primary nephrocytes through oxidative stress: Combined analysis at cellular and molecular levels

S Gao, M Jing, M Xu, D Han, Q Niu, R Liu - Journal of hazardous materials, 2020 - Elsevier
Long-chain perfluoroalkyl acids (PFAAs) such as perfluorodecanoic acid (PFDA) are toxic,
persistent organic pollutants. This study investigated the harmful effect of PFDA on mouse …

Simultaneous Over-Expression of PaSOD and RaAPX in Transgenic Arabidopsis thaliana Confers Cold Stress Tolerance through Increase in Vascular …

A Shafi, V Dogra, T Gill, PS Ahuja, Y Sreenivasulu - PloS one, 2014 - journals.plos.org
Antioxidant enzymes play a significant role in eliminating toxic levels of reactive oxygen
species (ROS), generated during stress from living cells. In the present study, two different …

Managing reactive oxygen species—Some learnings from high altitude extremophytes

A Kumar, S Guleria, D Ghosh, V Dogra… - … and Experimental Botany, 2021 - Elsevier
Oxygen (O 2) is an essential component of all living aerobic organisms. It acts as an
acceptor of energy and electrons during electron transport reactions, generating various …

[HTML][HTML] Improving the catalytic efficiency and dimeric stability of Cu, Zn superoxide dismutase by combining structure-guided consensus approach with site-directed …

S Kumar, VK Bhardwaj, S Guleria, R Purohit… - Biochimica et Biophysica …, 2022 - Elsevier
Superoxide dismutase (SOD) leads the front line of defense against injuries mediated by the
reactive oxygen species (ROS). The SOD from a high-altitude plant Potentilla atrosanguinea …