Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …
Biofabrication strategies for 3D in vitro models and regenerative medicine
Organs are complex systems composed of different cells, proteins and signalling molecules
that are arranged in a highly ordered structure to orchestrate a myriad of functions in our …
that are arranged in a highly ordered structure to orchestrate a myriad of functions in our …
[HTML][HTML] 3D bioprinting strategies, challenges, and opportunities to model the lung tissue microenvironment and its function
M Barreiro Carpio, M Dabaghi, J Ungureanu… - … in Bioengineering and …, 2021 - frontiersin.org
Human lungs are organs with an intricate hierarchical structure and complex composition;
lungs also present heterogeneous mechanical properties that impose dynamic stress on …
lungs also present heterogeneous mechanical properties that impose dynamic stress on …
Integrating organs-on-chips: multiplexing, scaling, vascularization, and innervation
Organs-on-chips (OoCs) have attracted significant attention because they can be designed
to mimic in vivo environments. Beyond constructing a single OoC, recent efforts have tried to …
to mimic in vivo environments. Beyond constructing a single OoC, recent efforts have tried to …
Organoid engineering with microfluidics and biomaterials for liver, lung disease, and cancer modeling
SK Kim, YH Kim, S Park, SW Cho - Acta biomaterialia, 2021 - Elsevier
As life expectancy improves and the number of people suffering from various diseases
increases, the need for developing effective personalized disease models is rapidly rising …
increases, the need for developing effective personalized disease models is rapidly rising …
Next generation organoids for biomedical research and applications
Organoids are in vitro cultures of miniature fetal or adult organ-like structures. Their
potentials for use in tissue and organ replacement, disease modeling, toxicology studies …
potentials for use in tissue and organ replacement, disease modeling, toxicology studies …
Building three-dimensional lung models for studying pharmacokinetics of inhaled drugs
AS Barros, A Costa, B Sarmento - Advanced drug delivery reviews, 2021 - Elsevier
Drug development is a critical step in the development pipeline of pharmaceutical industry,
commonly performed in traditional cell culture and animal models. Though, those models …
commonly performed in traditional cell culture and animal models. Though, those models …
Airway-on-a-chip: designs and applications for lung repair and disease
TJ Bennet, A Randhawa, J Hua, KC Cheung - Cells, 2021 - mdpi.com
The lungs are affected by illnesses including asthma, chronic obstructive pulmonary
disease, and infections such as influenza and SARS-CoV-2. Physiologically relevant models …
disease, and infections such as influenza and SARS-CoV-2. Physiologically relevant models …
Air quality effects on human health and approaches for its assessment through microfluidic chips
F Schulze, X Gao, D Virzonis, S Damiati, MR Schneider… - Genes, 2017 - mdpi.com
Air quality depends on the various gases and particles present in it. Both natural
phenomena and human activities affect the cleanliness of air. In the last decade, many …
phenomena and human activities affect the cleanliness of air. In the last decade, many …
New approach methods to evaluate health risks of air pollutants: Critical design considerations for in vitro exposure testing
Air pollution consists of highly variable and complex mixtures recognized as major
contributors to morbidity and mortality worldwide. The vast number of chemicals, coupled …
contributors to morbidity and mortality worldwide. The vast number of chemicals, coupled …