Abdominal aortic aneurysm: pathogenesis and implications for management

J Golledge, J Muller, A Daugherty… - … , and vascular biology, 2006 - Am Heart Assoc
Abdominal aortic aneurysm (AAA) affects approximately 5% of elderly men and is
responsible for a significant number of deaths in Western Countries. At present surgery by …

Abdominal aortic aneurysms: fresh insights from a novel animal model of the disease

MW Manning, LA Cassis, J Huang… - Vascular …, 2002 - journals.sagepub.com
Abdominal aortic aneurysms (AAA) have a high prevalence in aged populations and are
responsible for a large number of deaths. Despite the widespread nature of the disease …

[图书][B] Rutherford's vascular surgery e-book

JL Cronenwett, KW Johnston - 2014 - books.google.com
Published in association with the Society for Vascular Surgery, Rutherford's Vascular
Surgery presents state-of-the-art updates on all aspects of vascular health care. Extensively …

Angiotensin-converting enzyme inhibitors and aortic rupture: a population-based case-control study

DG Hackam, D Thiruchelvam, DA Redelmeier - The Lancet, 2006 - thelancet.com
Background Angiotensin-converting enzyme (ACE) inhibitors prevent the expansion and
rupture of aortic aneurysms in animals. We investigated the association between ACE …

The ACE gene insertion/deletion polymorphism and elite endurance swimming

G Tsianos, J Sanders, S Dhamrait, S Humphries… - European journal of …, 2004 - Springer
Human physical performance is influenced by genetic factors. A variation in the human
angiotensin I-converting enzyme (ACE) gene has been identified, in which the insertion (I) …

Abdominal aortic aneurysm as a complex multifactorial disease: interactions of polymorphisms of inflammatory genes, features of autoimmunity, and current status of …

WH Pearce, VP Shively - Annals of the New York Academy of …, 2006 - Wiley Online Library
The role of matrix metalloproteinases (MMPs) in the pathogenesis of abdominal aortic
aneurysm (AAA) has focused on the degradation of the extracellular matrix (ECM). The new …

Familial abdominal aortic aneurysms: collection of 233 multiplex families

H Kuivaniemi, H Shibamura, C Arthur, R Berguer… - Journal of vascular …, 2003 - Elsevier
Objective: This study investigated a large number of families in which at least two individuals
were diagnosed with abdominal aortic aneurysms to identify the relationship of the affected …

Mechanisms of abdominal aortic aneurysm formation

A Daugherty, LA Cassis - Current atherosclerosis reports, 2002 - Springer
Abdominal aortic aneurysms (AAA) are permanent dilations in the infra-renal area in which
the arterial tissue is characterized by inflammation and medial degeneration. AAAs are a …

[HTML][HTML] Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis

AR Thompson, F Drenos, H Hafez… - European Journal of …, 2008 - Elsevier
BACKGROUND: Candidate gene analysis has been frequently used in attempts to
understand the pathological processes involved in many aspects of AAA disease …

[HTML][HTML] The genetic basis of abdominal aortic aneurysms: a review

RM Sandford, MJ Bown, NJ London… - European Journal of …, 2007 - Elsevier
INTRODUCTION: The pathogenesis of abdominal aortic aneurysm (AAA) remains poorly
understood, however significant evidence has emerged in recent years to suggest a chronic …