Gut liver brain axis in diseases: the implications for therapeutic interventions

M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of spinocerebellar ataxia type 3

S Duarte-Silva, JD Da Silva… - The Journal of …, 2024 - Am Soc Clin Investig
Spinocerebellar ataxia type 3 (SCA3) is an adult-onset neurodegenerative disease caused
by a polyglutamine expansion in the ataxin-3 (ATXN3) gene. No effective treatment is …

[HTML][HTML] Gut-brain axis in the pathogenesis of sepsis-associated encephalopathy

X Wang, X Wen, S Yuan, J Zhang - Neurobiology of Disease, 2024 - Elsevier
The gut-brain axis is a bidirectional communication network linking the gut and the brain,
overseeing digestive functions, emotional responses, body immunity, brain development …

Regional and Conditional Variability of FXR: New lessons on Ileal Inflammation and Gut Barrier Functions

SA Joyce, D O'Malley - American Journal of Physiology …, 2024 - journals.physiology.org
Bile acids are amphipathic molecules synthesised in the liver and transported to the 21
small intestine, where they emulsify ingested lipids to facilitate enzymatic digestion and 22 …

[图书][B] Effects of FODMAPs and gluten on irritable bowel syndrome-from self-reported symptoms to molecular profiling

E Nordin - 2023 - search.proquest.com
Irritable bowel syndrome (IBS) is a complex disorder of gut-brain interactions. The diagnosis
of IBS is based on subjective reporting of abdominal pain and altered bowel habits in the …

Part A: Exploring How Those with Bile Acid Malabsorption (BAM) Experience their Wellbeing: An Interpretative Phenomenological Analysis using Photovoice Part B …

LJ Martin - 2024 - openresearch.surrey.ac.uk
(BAM) and Bile Acid Diarrhoea (BAD), specific GI conditions, on these outcomes. This thesis
aimed to understand the impact of BAM/BAD on mental health and wellbeing. Part one of …

Microbial metabolites as modulators of host physiology.

SA Joyce, DJ Clarke - Advances in Microbial Physiology, 2024 - europepmc.org
The gut microbiota is increasingly recognised as a key player in influencing human health
and changes in the gut microbiota have been strongly linked with many non-communicable …

Perspectives of ursodeoxycholic acid application in clinical practice

AM Morozov, AV Kadykov, NA Sergeev… - Vrach, 2024 - journals.eco-vector.com
The possibilities of ursodeoxycholic acid (UDCA) application in clinical practice are
evaluated. Statistical analysis of data from modern Russian and foreign literature sources …

Hepatic interoception in health and disease

HR Berthoud, H Münzberg, CD Morrison… - Autonomic …, 2024 - Elsevier
The liver is a large organ with crucial functions in metabolism and immune defense, as well
as blood homeostasis and detoxification, and it is clearly in bidirectional communication with …