Presence of pharmaceuticals and their metabolites in wild-living aquatic organisms–current state of knowledge

K Świacka, J Maculewicz, D Kowalska, M Caban… - Journal of Hazardous …, 2022 - Elsevier
In the last decades an increasing number of studies has been published concerning
contamination of aquatic ecosystems with pharmaceuticals. Yet, the distribution of these …

Sorption of pharmaceuticals on the surface of microplastics

A Puckowski, W Cwięk, K Mioduszewska… - Chemosphere, 2021 - Elsevier
The presence of both pollutants: microplastics and pharmaceutical residues in various
environmental compartments is an issue of increasing concern. Available literature data …

Multifunctional gold nanoclusters for effective targeting, near-infrared fluorescence imaging, diagnosis, and treatment of cancer lymphatic metastasis

Z Pang, W Yan, J Yang, Q Li, Y Guo, D Zhou, X Jiang - ACS nano, 2022 - ACS Publications
Developing effective lymph-node (LN) targeting and imaging probes is crucial for the early
detection and diagnosis of tumor metastasis to improve patient survival. Most current clinical …

Oxidation processes for cytostatic drugs elimination in aqueous phase: A critical review

AL Garcia-Costa, A Alves, LM Madeira… - Journal of Environmental …, 2021 - Elsevier
Cancer is one of the deadliest diseases nowadays. With a continuous growth in cancer-
affected patients, the consumption of cytostatic drugs in chemotherapy is also increasing. As …

In situ growth of metal–organic framework HKUST-1 on graphene oxide nanoribbons with high electrochemical sensing performance in imatinib determination

N Rezvani Jalal, T Madrakian, A Afkhami… - … applied materials & …, 2020 - ACS Publications
Metal–organic frameworks (MOFs) have been previously investigated as electrode materials
for developing electrochemical sensors. They have usually been reported to suffer from poor …

Methotrexate detection in serum at clinically relevant levels with electrochemically assisted SERS on a benchtop, custom built Raman spectrometer

Y Goksel, E Dumont, R Slipets, ST Rajendran… - ACS …, 2022 - ACS Publications
Therapeutic drug monitoring (TDM) is an essential clinical practice for optimizing drug
dosing, thereby preventing adverse effects of drugs with a narrow therapeutic window, slow …

Nanoencapsulation of aptamer-functionalized 5-Fluorouracil liposomes using alginate/chitosan complex as a novel targeting strategy for colon-specific drug delivery

M Khodarahmi, H Abbasi, M Kouchak… - Journal of Drug Delivery …, 2022 - Elsevier
Two important challenges in clinical application of 5-Fluorouracil (5-FU) in the treatment of
colon cancer are preventing the release or degradation of the drug in the stomach/small …

Cocrystallization of 5-fluorouracil with gallic acid: A novel 5-fluorouracil cocrystal displaying synergistic anti-tumor activity both in oral and intraperitoneal injection …

H Hao, Y Zhang, X Hu, W Guo, C Yang… - European Journal of …, 2023 - Elsevier
Gallic acid (GA) is a naturally occurring polyphenolic compound exhibiting anti-tumor
activity. To clarify the capability of GA in optimizing the in vitro/in vivo properties of the first …

Ionic liquids with methotrexate moieties as a potential anticancer prodrug: Synthesis, characterization and solubility evaluation

RM Moshikur, MR Chowdhury, R Wakabayashi… - Journal of Molecular …, 2019 - Elsevier
The technological utility of active pharmaceutical ingredients (APIs) is enormously improved
when they are converted into ionic liquids (ILs). API-ILs possess better aqueous solubility …

Adsorption of doxorubicin and 5-Fluorouracil anticancer drugs from aqueous media using MIL-101-NH2 (Co/Fe) bi-metal–organic framework

LR Rad, H Faramarzi, M Anbia, M Irani - Separation and Purification …, 2024 - Elsevier
In the present study, the MIL-101-NH 2 (Fe) metal–organic frameworks (MOFs) and MIL-101-
NH 2 (Co/Fe) bi-metal–organic frameworks were synthesized using solvothermal method …