The immunology of systemic lupus erythematosus

GC Tsokos - Nature Immunology, 2024 - nature.com
Understanding the pathogenesis and clinical manifestations of systemic lupus
erythematosus (SLE) has been a great challenge. Reductionist approaches to understand …

Interplay between T-bet and HIF-1a is required for proper epigenomic and transcriptomic reprogramming of monocyte subsets

A Ferreté-Bonastre, O Morante-Palacios… - 2024 - researchsquare.com
Background: Monocyte subsets, classified into classical, intermediate, and non-classical,
have distinct specific functions. Despite increasing reports describing changes in monocyte …