Nonthermal irreversible electroporation: fundamentals, applications, and challenges

A Golberg, ML Yarmush - IEEE Transactions on biomedical …, 2013 - ieeexplore.ieee.org
Tissue ablation is an essential procedure for the treatment of many diseases. In the last
decade, a nonthermal tissue ablation using intensive pulsed electric fields, called …

Physical methods for genetic plant transformation

AL Rivera, M Gómez-Lim, F Fernández, AM Loske - Physics of life reviews, 2012 - Elsevier
Production of transgenic plants is a routine process for many crop species. Transgenes are
introduced into plants to confer novel traits such as improved nutritional qualities, tolerance …

Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery

M Han, L Chen, K Aras, C Liang, X Chen… - Nature biomedical …, 2020 - nature.com
The rigidity and relatively primitive modes of operation of catheters equipped with sensing or
actuation elements impede their conformal contact with soft-tissue surfaces, limit the scope …

Integrated, transparent silicon carbide electronics and sensors for radio frequency biomedical therapy

TK Nguyen, S Yadav, TA Truong, M Han, M Barton… - ACS …, 2022 - ACS Publications
The integration of micro-and nanoelectronics into or onto biomedical devices can facilitate
advanced diagnostics and treatments of digestive disorders, cardiovascular diseases, and …

Mitigation of impedance changes due to electroporation therapy using bursts of high-frequency bipolar pulses

SP Bhonsle, CB Arena, DC Sweeney… - Biomedical engineering …, 2015 - Springer
Background For electroporation-based therapies, accurate modeling of the electric field
distribution within the target tissue is important for predicting the treatment volume. In …

A three-dimensional in vitro tumor platform for modeling therapeutic irreversible electroporation

CB Arena, CS Szot, PA Garcia, MN Rylander… - Biophysical journal, 2012 - cell.com
Irreversible electroporation (IRE) is emerging as a powerful tool for tumor ablation that
utilizes pulsed electric fields to destabilize the plasma membrane of cancer cells past the …

Cell membrane electroporation-Part 2: the applications

S Haberl, D Miklavcic, G Sersa, W Frey… - IEEE Electrical …, 2013 - ieeexplore.ieee.org
Cell membrane electroporation-Part 2: the applications Page 1 January/February — Vol. 29,
No. 1 29 FEATUREARTICLE Cell Membrane Electroporation— Part 2: The Applications Key …

MRI study on reversible and irreversible electroporation induced blood brain barrier disruption

M Hjouj, D Last, D Guez, D Daniels, S Sharabi, J Lavee… - 2012 - journals.plos.org
Electroporation, is known to induce cell membrane permeabilization in the reversible (RE)
mode and cell death in the irreversible (IRE) mode. Using an experimental system designed …

Advantages and disadvantages of different concepts of electroporation pulse generation

M Reberšek, D Miklavčič - Automatika, 2011 - Taylor & Francis
Electroporator is a generator of electric pulses that is used for permeabilization of cells.
There are five major concepts of electroporation design. Capacitor discharge, square wave …

Determinants of acute irreversible electroporation lesion characteristics after pulsed field ablation: the role of voltage, contact, and adipose interference

A Gasperetti, F Assis, H Tripathi, M Suzuki… - Europace, 2023 - academic.oup.com
Aims Pulsed field ablation (PFA) is a non-thermal ablative approach in which cardiomyocyte
death is obtained through irreversible electroporation (IRE). Data correlating the biophysical …