Soft‐tissue sarcoma in adults: an update on the current state of histiotype‐specific management in an era of personalized medicine

AC Gamboa, A Gronchi… - CA: a cancer journal for …, 2020 - Wiley Online Library
Soft‐tissue sarcomas (STS) are rare tumors that account for 1% of all adult malignancies,
with over 100 different histologic subtypes occurring predominately in the trunk, extremity …

Desmoid tumors: a comprehensive review

M Bektas, T Bell, S Khan, B Tumminello… - Advances in …, 2023 - Springer
Desmoid tumors (DT) are rare, locally aggressive, fibroblastic soft-tissue tumors that are
characterized by infiltrative growth and can affect organs and adjacent structures, resulting …

Nirogacestat, a γ-secretase inhibitor for desmoid tumors

M Gounder, R Ratan, T Alcindor… - … England Journal of …, 2023 - Mass Medical Soc
Background Desmoid tumors are rare, locally aggressive, highly recurrent soft-tissue tumors
without approved treatments. Methods We conducted a phase 3, international, double-blind …

[HTML][HTML] Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

A Gronchi, AB Miah, AP Dei Tos, N Abecassis… - Annals of …, 2021 - Elsevier
Highlights•This Clinical Practice Guideline provides key recommendations on the
management of soft tissue and visceral sarcomas.•Recommendations have been agreed …

NCCN guidelines insights: soft tissue sarcoma, version 1.2021: featured updates to the NCCN guidelines

M von Mehren, JM Kane, MM Bui, E Choy… - Journal of the National …, 2020 - jnccn.org
The NCCN Guidelines for Soft Tissue Sarcoma provide recommendations for the diagnosis,
evaluation, treatment, and follow-up for patients with soft tissue sarcomas. These NCCN …

[HTML][HTML] Expert consensus on resection of chest wall tumors and chest wall reconstruction

L Wang, X Yan, J Zhao, C Chen, C Chen… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Chest wall tumors are a relatively uncommon disease in clinical practice. Most of the
published studies about chest wall tumors are usually single-center retrospective studies …

Evolving strategies for management of desmoid tumor

RF Riedel, M Agulnik - Cancer, 2022 - Wiley Online Library
Desmoid tumors (DTs) are rare soft tissue mesenchymal neoplasms that may be associated
with impairments, disfigurement, morbidity, and (rarely) mortality. DT disease course can be …

Molecular pathogenesis of desmoid tumor and the role of γ-secretase inhibition

N Federman - NPJ precision oncology, 2022 - nature.com
Desmoid tumor (DT) is a rare, soft tissue neoplasm associated with an unpredictable clinical
course. Although lacking metastatic potential, DT is often locally aggressive and invasive …

Desmoid tumors: to treat or not to treat, that is the question

B Kasper, CP Raut, A Gronchi - Cancer, 2020 - Wiley Online Library
Desmoid tumors (DTs) are a rare disease of intermediate malignancy characterized
histologically by a locally aggressive, monoclonal, fibroblastic proliferation and clinically by …

[PDF][PDF] Pediatric non-rhabdomyosarcoma soft tissue sarcomas: standard of care and treatment recommendations from the European Paediatric Soft Tissue Sarcoma …

A Ferrari, B Brennan, M Casanova… - Cancer Management …, 2022 - Taylor & Francis
This paper describes the standard of care for patients with non-rhabdomyosarcoma soft
tissue sarcomas (NRSTS) and the therapeutic recommendations developed by the …