Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

M Solmi, M De Toffol, JY Kim, MJ Choi, B Stubbs… - bmj, 2023 - bmj.com
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …

Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis

N Black, E Stockings, G Campbell, LT Tran… - The Lancet …, 2019 - thelancet.com
Background Medicinal cannabinoids, including medicinal cannabis and pharmaceutical
cannabinoids and their synthetic derivatives, such as tetrahydrocannabinol (THC) and …

Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications

DF Levey, M Galimberti, JD Deak, FR Wendt… - Nature Genetics, 2023 - nature.com
As recreational use of cannabis is being decriminalized in many places and medical use
widely sanctioned, there are growing concerns about increases in cannabis use disorder …

Complex regional pain syndrome: a comprehensive review

SS Taylor, N Noor, I Urits, A Paladini, MS Sadhu… - Pain and therapy, 2021 - Springer
Complex regional pain syndrome (CRPS) is a chronic pain condition often involving
hyperalgesia and allodynia of the extremities. CRPS is divided into CRPS-I and CRPS-II …

Cannabis-based products for chronic pain: a systematic review

MS McDonagh, BJ Morasco, J Wagner… - Annals of internal …, 2022 - acpjournals.org
Background: Contemporary data are needed about the utility of cannabinoids in chronic
pain. Purpose: To evaluate the benefits and harms of cannabinoids for chronic pain. Data …

Early evidence of the impact of cannabis legalization on cannabis use, cannabis use disorder, and the use of other substances: Findings from state policy evaluations

R Smart, RL Pacula - The American journal of drug and alcohol …, 2019 - Taylor & Francis
Background: The past decade has seen unprecedented shifts in the cannabis policy
environment, and the public health impacts of these changes will hinge on how they affect …

Public health implications of legalising the production and sale of cannabis for medicinal and recreational use

W Hall, D Stjepanović, J Caulkins, M Lynskey, J Leung… - The Lancet, 2019 - thelancet.com
We assess the current and describe possible future public health impacts of the legalisation
of cannabis production, sale, and use in the Americas. First, we describe global patterns of …

[HTML][HTML] An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia

T van de Donk, M Niesters, MA Kowal, E Olofsen… - Pain, 2019 - journals.lww.com
In this experimental randomized placebo-controlled 4-way crossover trial, we explored the
analgesic effects of inhaled pharmaceutical-grade cannabis in 20 chronic pain patients with …

The effectiveness of topical cannabidiol oil in symptomatic relief of peripheral neuropathy of the lower extremities

DH Xu, BD Cullen, M Tang… - Current pharmaceutical …, 2020 - benthamdirect.com
Background: Peripheral neuropathy can significantly impact the quality of life for those who
are affected, as therapies from the current treatment algorithm often fail to deliver adequate …

Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention

ND Volkow, C Blanco - World Psychiatry, 2023 - Wiley Online Library
Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …