Life, death and autophagy
J Doherty, EH Baehrecke - Nature cell biology, 2018 - nature.com
Autophagy influences cell survival through maintenance of cell bioenergetics and clearance
of protein aggregates and damaged organelles. Several lines of evidence indicate that …
of protein aggregates and damaged organelles. Several lines of evidence indicate that …
Neutrophil extracellular traps (NETs) and damage‐associated molecular patterns (DAMPs): two potential targets for COVID‐19 treatment
S Cicco, G Cicco, V Racanelli… - Mediators of …, 2020 - Wiley Online Library
COVID‐19 is a pandemic disease caused by the new coronavirus SARS‐CoV‐2 that mostly
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …
affects the respiratory system. The consequent inflammation is not able to clear viruses. The …
Autophagy induction promoted by m6A reader YTHDF3 through translation upregulation of FOXO3 mRNA
WC Hao, MJ Dian, Y Zhou, QL Zhong, WQ Pang… - Nature …, 2022 - nature.com
Autophagy is crucial for maintaining cellular energy homeostasis and for cells to adapt to
nutrient deficiency, and nutrient sensors regulating autophagy have been reported …
nutrient deficiency, and nutrient sensors regulating autophagy have been reported …
Autophagy—cell survival and death
X Yan, R Zhou, Z Ma - Autophagy: Biology and Diseases: Basic Science, 2019 - Springer
Autophagy, which is one of the most important ways to maintain cell homeostasis plays an
important regulatory role in cell survival and death. Currently, it is agreed that autophagy …
important regulatory role in cell survival and death. Currently, it is agreed that autophagy …
B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction
T Minato, S Nirasawa, T Sato, T Yamaguchi… - Nature …, 2020 - nature.com
Abstract Angiotensin-converting enzyme 2 (ACE2) is critically involved in cardiovascular
physiology and pathology, and is currently clinically evaluated to treat acute lung failure …
physiology and pathology, and is currently clinically evaluated to treat acute lung failure …
Intersections between regulated cell death and autophagy
In multicellular organisms, cell death is an essential aspect of life. Over the past decade, the
spectrum of different forms of regulated cell death (RCD) has expanded dramatically with …
spectrum of different forms of regulated cell death (RCD) has expanded dramatically with …
The regulatory properties of the Ccr4–Not complex
N Chalabi Hagkarim, RJ Grand - Cells, 2020 - mdpi.com
The mammalian Ccr4–Not complex, carbon catabolite repression 4 (Ccr4)-negative on
TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts …
TATA-less (Not), is a large, highly conserved, multifunctional assembly of proteins that acts …
m6A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis
Y Nagaki, S Motoyama, T Yamaguchi… - Genes to …, 2020 - Wiley Online Library
Esophageal squamous cell carcinoma (ESCC) is one of the most fatal types of malignant
tumors worldwide. Epitranscriptome, such as N6‐methyladenosine (m6A) of mRNA, is an …
tumors worldwide. Epitranscriptome, such as N6‐methyladenosine (m6A) of mRNA, is an …
Post-transcriptional dynamics and RNA homeostasis in autophagy and cancer
SP Kolapalli, TM Nielsen, LB Frankel - Cell Death & Differentiation, 2023 - nature.com
Autophagy is an essential recycling and quality control pathway which preserves cellular
and organismal homeostasis. As a catabolic process, autophagy degrades damaged and …
and organismal homeostasis. As a catabolic process, autophagy degrades damaged and …
[HTML][HTML] The pleiotropy associated with de novo variants in CHD4, CNOT3, and SETD5 extends to moyamoya angiopathy
Purpose Moyamoya angiopathy (MMA) is a cerebrovascular disease characterized by
occlusion of large arteries, which leads to strokes starting in childhood. Twelve altered …
occlusion of large arteries, which leads to strokes starting in childhood. Twelve altered …