Crosstalk involving two-component systems in Staphylococcus aureus signaling networks

L Ali, MH Abdel Aziz - Journal of Bacteriology, 2024 - Am Soc Microbiol
Staphylococcus aureus poses a serious global threat to human health due to its pathogenic
nature, adaptation to environmental stress, high virulence, and the prevalence of …

The Staphylococcus aureus ArlS Kinase Inhibitor Tilmicosin Has Potent Anti-Biofilm Activity in Both Static and Flow Conditions

Z Wang, H Wang, J Bai, S Cai, D Qu, Y Xie, Y Wu - Microorganisms, 2024 - mdpi.com
Staphylococcus aureus can form biofilms on biotic surfaces or implanted materials, leading
to biofilm-associated diseases in humans and animals that are refractory to conventional …

A benzoxazolylurea inhibits VraS and enhances antimicrobials against vancomycin intermediate-resistant Staphylococcus aureus

A Sarkar, MH Abdelaziz, EP Heckler, L Ali… - bioRxiv, 2023 - biorxiv.org
Vancomycin intermediate-resistant Staphylococcus aureus (VISA) is a pathogen of concern.
VraS, a histidine kinase, facilitates the VISA phenotype. Here, we reveal a benzoxazolylurea …

[引用][C] Drug repurposing for bacterial infections

M Ilyas, MS Latif, A Gul, MM Babar, J Rajadas - 2024 - Elsevier