Information on drug absorption and disposition in infants and children has increased
considerably over the past 2 decades. However, the impact of specific age-related effects on …

The liver plays critical roles in both homeostasis and pathology. It is the major site of drug
metabolism in the body and, as such, a common target for drug-induced toxicity and is …

A number of anatomical and physiological factors determine the pharmacokinetic profile of a
drug. Differences in physiology in paediatric populations compared with adults can influence …

Written by experienced and internationally renowned contributors, this is the fourth edition of
what has become the standard reference for cosmetic scientists and dermatologists seeking …

Secondhand smoke exposure (SHSe) is a known cause of many adverse health effects in
adults and children. Increasingly, SHSe assessment is an element of tobacco control …

Infants and children are not little adults. They are uniquely vulnerable to environmental
toxicants. To protect infants and children against toxicants, the National Research Council in …

The approach to paediatric drug dosing needs to be based on the physiological
characteristics of the child and the pharmacokinetic parameters of the drug. This review …

The thousands of chemicals present in the environment (USGAO, 2013) must be triaged to
identify priority chemicals for human health risk research. Most chemicals have little of the …

The occurrences of mycotoxins as food contaminants in different localities particularly in
developing countries and the inevitable exposure of populations and children to these toxins …

Following a request from the European Commission to EFSA, the EFSA Scientific Committee
(SC) prepared a guidance for the risk assessment of substances present in food intended for …