EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

[HTML][HTML] Cadmium exposure inhibits MMP2 and MMP9 activities in the prostate and testis

LM Lacorte, JC Rinaldi, LA Justulin Jr… - Biochemical and …, 2015 - Elsevier
Matrix metalloproteinases (MMPs) are zinc (Zn 2+) and calcium (Ca 2+) dependant
endopeptidases, capable of degradation of numerous components of the extracellular …

Caffeine reduces cadmium accumulation in the organism and enhances the levels of antioxidant protein expression in the epididymis

LM Lacorte, FRF Seiva, JC Rinaldi, FK Delella… - Reproductive …, 2013 - Elsevier
The aim of this study was to investigate the effects of caffeine (20mg/L) intake on cadmium
(15mg/L) accumulation in the rat blood, testes, epididymis and prostate as well as cadmium …

Chronic caffeine intake increases androgenic stimuli, epithelial cell proliferation and hyperplasia in rat ventral prostate

C Sarobo, LM Lacorte, M Martins… - International Journal …, 2012 - Wiley Online Library
Coffee intake has been associated with a low risk of developing cancer, including prostate
cancer, which is one of the most commonly diagnosed cancer in men. However, few studies …

Impacts of heavy metal exposure on the prostate of murine models: Mechanisms of toxicity

SB Silva, TFR Ruiz, FCA Dos Santos, SR Taboga… - Reproductive …, 2023 - Elsevier
Heavy metals are elements found into the environment mainly due to anthropogenic
activities. Naturally occurring and higher released doses cause disorders in the prostate …

[HTML][HTML] Neuroendocrine effects of cadmium exposure on male reproductive functions

M Arteaga-Silva, E Arenas-Rios… - Frontiers in Bioscience …, 2020 - imrpress.com
In industrialized countries, the use of Cadmium (Cd) produces a form of anthropogenic
pollution. Hence, exposure by human populations is becoming a public health problem. With …

Association between cadmium and androgen receptor protein expression differs in prostate tumors of African American and European American men

CM Neslund-Dudas, RB McBride… - Journal of Trace …, 2018 - Elsevier
Cadmium is a known carcinogen that has been implicated in prostate cancer, but how it
affects prostate carcinogenesis in humans remains unclear. Evidence from basic science …

Long‐term effects of perinatal exposure to low doses of cadmium on the prostate of adult male rats

VP Santana, ÉS Salles, DE Correa… - International journal …, 2016 - Wiley Online Library
Developmental toxicity caused by environmental exposure to heavy metals during the
perinatal period has raised questions about offspring health. Cadmium (Cd) is an endocrine …

Delay in puberty indices of Wistar rats caused by cadmium. Focus on the redox system in reproductive organs

J Hernández-Rodríguez, AL López, S Montes… - Reproductive …, 2021 - Elsevier
Puberty is a transitional period from juvenile stage to adulthood, followed by the functional
maturation of gonads and reproductive organs. This period is sensitive to environmental …

DNA fragmentation, caspase 3 and prostate-specific antigen genes expression induced by arsenic, cadmium, and chromium on nontumorigenic human prostate cells

HMA El-Atta, AA El-Bakary, AM Attia, A Lotfy… - Biological trace element …, 2014 - Springer
Prostate cancer is one of the most common cancers and the second cause of cancer-related
deaths among men. Metals are recognized as chemical carcinogens where chronic …