From genetic mosaicism to tumorigenesis through indirect genetic effects

JP Capp, F Catania, F Thomas - BioEssays, 2024 - Wiley Online Library
Genetic mosaicism has long been linked to aging, and several hypotheses have been
proposed to explain the potential connections between mosaicism and susceptibility to …

Graphene-Based Photodynamic Therapy and Overcoming Cancer Resistance Mechanisms: A Comprehensive Review

H Dilenko, K Bartoň Tománková, L Válková… - International Journal …, 2024 - Taylor & Francis
Photodynamic therapy (PDT) is a non-invasive therapy that has made significant progress in
treating different diseases, including cancer, by utilizing new nanotechnology products such …

[PDF][PDF] Oncotherapy resistance explained by Darwinian and Lamarckian models

Y Saunthararajah - Journal of Clinical Investigation, 2024 - Am Soc Clin Investig
Cell and antibody therapies directed against surface molecules on B cells, eg, CD19-
targeting chimeric antigen receptor T cells (CD19 CAR-T), are now standard for patients with …

Evolution of small cell lung cancer tumor mutation: from molecular mechanisms to novel viewpoints

X Guan, G Bao, J Liang, Y Yao, Y Xiang… - Seminars in Cancer …, 2022 - Elsevier
Small cell lung cancer (SCLC) is a clinically common malignant tumor originating from the
lung neuroendocrine stem cells, which has a poor prognosis and accounts for approximately …

Is Cancer Metabolism an Atavism?

E Fanchon, A Stéphanou - Cancers, 2024 - mdpi.com
Simple Summary The atavistic theory of cancer suggests that cancer development proceeds
through cells reverting to ancient survival mechanisms. The Serial Atavism Model (SAM) …

One Cell, Two Gears: Extensive Somatic Genome Plasticity Accompanies High Germline Genome Stability in Paramecium

F Catania, R Rothering, V Vitali - Genome Biology and Evolution, 2021 - academic.oup.com
Mutation accumulation (MA) experiments are conventionally employed to study
spontaneous germline mutations. However, MA experiments can also shed light on somatic …

Comments on “Bridging Tumorigenesis and Therapy Resistance With a Non-Darwinian and Non-Lamarckian Mechanism of Adaptive Evolution”

M Tez - Frontiers in Oncology, 2021 - frontiersin.org
I have read the hypothesis article entitled “Bridging Tumorigenesis and Therapy Resistance
With a Non-Darwinian and Non-Lamarckian Mechanism of Adaptive Evolution” with great …

[PDF][PDF] оптимизация стратегии терапии с учетом эволюции опухолевого роста

ВА Чубенко - 2023 - practical-oncology.ru
В клинической практике оптимальная стратегия терапии, безусловно, построена на
понимании биологии опухолевого роста, современное представление о котором …

[HTML][HTML] Is Cancer an Example of Evolution?

J Bergman - crev.info
Cancer is the result of breaking genes, which happens when mutations strike. An oft-
repeated claim by those who support Darwinism is that knowledge of the theory of evolution …

[HTML][HTML] Mutations Destroy Evolution

J Bergman - crev.info
New research has determined that even a larger number of intergenetic connections in
humans exist than assumed previously, documenting greater levels of genetic complexity …