Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …

A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …

Age‐related macular degeneration (AMD) is a common cause of visual impairment in the
elderly. There are very limited therapeutic options for AMD with the predominant therapies …

There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

Age related macular degeneration (AMD) is the leading cause of vision loss of those over
the age of 65 in the industrialized world. The prevalence and need to develop effective …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Complement factor H (CFH) is a major susceptibility gene for age-related macular
degeneration (AMD); however, its impact on AMD pathobiology is unresolved. Here, the role …

The physiological role of autophagic flux within the vascular endothelial layer remains
poorly understood. Here, we show that in primary endothelial cells, oxidized and native LDL …

CD36 is a multiligand receptor contributing to glucose and lipid metabolism, immune
response, inflammation, thrombosis, and fibrosis. A wide range of tissue expression includes …