Metabolic syndrome (MS) is a condition that includes obesity, insulin resistance,
dyslipidemias among other, abnormalities that favors type 2 Diabetes Mellitus (T2DM) and …

Nerve growth factor (NGF) was the first neurotrophin described. This neurotrophin
contributes to organogenesis by promoting sensory innervation and angiogenesis in the …

Metabolic syndrome (MS) is a cluster of signs that increases the risk to develop diabetes
mellitus type 2 and cardiovascular disease. In the last years, a growing interest to study the …

Bone mineral, adipose tissue and energy metabolism are interconnected by a complex and
multilevel series of networks. Calcium and phosphorus are utilized for insulin secretion and …

Objective: We assessed the sex-specific differences in the molecular mechanisms of insulin
resistance in muscle and adipose tissue, in a MS rat model induced by a high sucrose diet …

Inwardly rectifying potassium (Kir) channels play a key role in maintaining the resting
membrane potential and supporting potassium homeostasis. There are many variants of Kir …

Secretion of insulin from pancreatic β-cells is complex, but physiological glucose-dependent
secretion is dominated by electrical activity, in turn controlled by ATP-sensitive potassium …

Pancreatic beta cells, unique cells that secrete insulin in response to an increase in glucose
levels, play a significant role in glucose homeostasis. Glucose-stimulated insulin secretion …

Cystic fibrosis (CF) is due to mutations in the CF-transmembrane conductance regulator
(CFTR) and CF-related diabetes (CFRD) is its most common co-morbidity, affecting~ 50% of …

Transient receptor potential (TRP) channels have shown to be involved in a wide variety of
physiological functions and pathophysiological conditions. Modulation of TRP channels …