Role of intracellular complement activation in kidney fibrosis
D Portilla, S Xavier - British journal of pharmacology, 2021 - Wiley Online Library
Increased expression of complement C1r, C1s and C3 in kidney cells plays an important
role in the pathogenesis of kidney fibrosis. Our studies suggest that activation of complement …
role in the pathogenesis of kidney fibrosis. Our studies suggest that activation of complement …
Acute skin exposure to ultraviolet light triggers neutrophil-mediated kidney inflammation
S Skopelja-Gardner, J Tai, X Sun… - Proceedings of the …, 2021 - National Acad Sciences
Photosensitivity to ultraviolet (UV) light affects up to∼ 80% of lupus patients. Sunlight
exposure can exacerbate local as well as systemic manifestations of lupus, including …
exposure can exacerbate local as well as systemic manifestations of lupus, including …
[HTML][HTML] C1q as a target molecule to treat human disease: What do mouse studies teach us?
K Schulz, M Trendelenburg - Frontiers in Immunology, 2022 - frontiersin.org
The complement system is a field of growing interest for pharmacological intervention.
Complement protein C1q, the pattern recognition molecule at the start of the classical …
Complement protein C1q, the pattern recognition molecule at the start of the classical …
Group 3 innate lymphoid cells exacerbate lupus nephritis by promoting B cell activation in kidney ectopic lymphoid structures
F Li, Z Liang, H Zhong, X Hu, Z Tang, C Zhu… - Advanced …, 2023 - Wiley Online Library
Group 3 innate lymphoid cells (ILC3s) represent a new population in immune regulation, yet
their role in lupus nephritis (LN) remains elusive. In the present work, systemic increases in …
their role in lupus nephritis (LN) remains elusive. In the present work, systemic increases in …