Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …

Toxoplasma gondii can infect homoeothermic animals including humans and cause lethal
toxoplasmosis in immunocompromised individuals. When hosts are infected with T. gondii …

An early hallmark of Toxoplasma gondii infection is the rapid control of the parasite
population by a potent multifaceted innate immune response that engages resident and …

Pathogens secrete effector proteins to subvert host physiology and cause disease. Effectors
are engaged in a molecular arms race with the host resulting in conflicting evolutionary …

Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host
range, including humans, across the globe. The outcome of infection differs remarkably …

The Polycomb group of proteins is required for the proper orchestration of gene expression
due to its role in maintaining transcriptional silencing. It is composed of several chromatin …

Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates
within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite …

Malaria infection renders humans more attractive to Anopheles gambiae sensu lato
mosquitoes than uninfected people. The mechanisms remain unknown. We found that an …

Toxoplasma gondii and Plasmodium species are obligatory intracellular parasites that
export proteins into the infected cells in order to interfere with host‐signalling pathways …

Abstract Background Lysine lactylation (Kla) is a novelposttranslational modification (PTM)
identified in histone and nonhistone proteins of several eukaryotic cells that directly activates …