Combating melanoma: The use of photodynamic therapy as a novel, adjuvant therapeutic tool
LM Davids, B Kleemann - Cancer treatment reviews, 2011 - Elsevier
Metastatic malignant melanoma remains one of the most dreaded skin cancers worldwide.
Numerous factors contribute to its resistance to hosts of treatment regimes and despite …
Numerous factors contribute to its resistance to hosts of treatment regimes and despite …
The multifaceted photocytotoxic profile of hypericin
TA Theodossiou, JS Hothersall… - Molecular …, 2009 - ACS Publications
Photodynamic therapy (PDT) is an established anticancer treatment employing a phototoxin
(photosensitizer), visible light and oxygen. The latter is photochemically converted into …
(photosensitizer), visible light and oxygen. The latter is photochemically converted into …
Bladder organoids and spheroids: potential tools for normal and diseased tissue modelling
I Vasyutin, L Zerihun, C Ivan, A Atala - Anticancer Research, 2019 - ar.iiarjournals.org
Bladder-related diseases are among the most common and costly to the healthcare system,
and therefore require new approaches to treatment. Organoids and spheroids are 3D …
and therefore require new approaches to treatment. Organoids and spheroids are 3D …
Hypericin-photodynamic therapy leads to interleukin-6 secretion by HepG2 cells and their apoptosis via recruitment of BH3 interacting-domain death agonist and …
Photodynamic therapy (PDT) has emerged as a capable therapeutic modality for the
treatment of cancer. PDT is a targeted cancer therapy that reportedly leads to tumor cell …
treatment of cancer. PDT is a targeted cancer therapy that reportedly leads to tumor cell …
Perspectives on the application of nanotechnology in photodynamic therapy for the treatment of melanoma
V Monge-Fuentes, LA Muehlmann, RB de Azevedo - Nano reviews, 2014 - Taylor & Francis
Malignant melanoma is the most aggressive form of skin cancer and has been traditionally
considered difficult to treat. The worldwide incidence of melanoma has been increasing …
considered difficult to treat. The worldwide incidence of melanoma has been increasing …
Metabarcoding Reveals Temporal Patterns of Community Composition and Realized Thermal Niches of Thalassiosira Spp. (Bacillariophyceae) from the Narragansett …
Diatoms generate nearly half of marine primary production and are comprised of a diverse
array of species that are often morphologically cryptic or difficult to identify using light …
array of species that are often morphologically cryptic or difficult to identify using light …
Hypericin-photodynamic therapy induces human umbilical vein endothelial cell apoptosis
The conventional photosensitizers used in photodynamic therapy (PDT), such as
haematoporphyrin (HP), have not yet reached satisfactory therapeutic effects on port-wine …
haematoporphyrin (HP), have not yet reached satisfactory therapeutic effects on port-wine …
Accumulation and penetration behavior of hypericin in glioma tumor spheroids studied by fluorescence microscopy and confocal fluorescence lifetime imaging …
MC Bassler, T Rammler, F Wackenhut… - Analytical and …, 2022 - Springer
Glioblastoma WHO IV belongs to a group of brain tumors that are still incurable. A promising
treatment approach applies photodynamic therapy (PDT) with hypericin as a …
treatment approach applies photodynamic therapy (PDT) with hypericin as a …
MPEG‐hexPLA micelles as novel carriers for hypericin, a fluorescent marker for use in cancer diagnostics
K Mondon, M Zeisser‐Labouèbe… - Photochemistry and …, 2011 - Wiley Online Library
Ovarian cancer is the most common gynecological cancer diagnosed in Western countries.
Detection of micrometastases at an early stage of the disease could lead to a cure rate of …
Detection of micrometastases at an early stage of the disease could lead to a cure rate of …
A model in vitro study using hypericin: tumor-versus necrosis-targeting property and possible mechanisms
Y Li, S Wang, Y Zhao, H Saiyin, X He, J Zhao, L Li… - Biology, 2020 - mdpi.com
Hypericin (Hyp) had been explored as a tumor-seeking agent for years; however, more
recent studies showed its necrosis-avidity rather than cancer-seeking property. To further …
recent studies showed its necrosis-avidity rather than cancer-seeking property. To further …