[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …
important roles in many physiological and pathological processes. EVs enable intercellular …
Extracellular vesicles in the tumor microenvironment: old stories, but new tales
L Han, EWF Lam, Y Sun - Molecular cancer, 2019 - Springer
Mammalian cells synthesize and release heterogeneous extracellular vesicles (EVs) which
can be generally recognized as subclasses including exosomes, microvesicles (MVs), and …
can be generally recognized as subclasses including exosomes, microvesicles (MVs), and …
Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles
Z Wei, X Zhang, T Yong, N Bie, G Zhan, X Li… - Nature …, 2021 - nature.com
The main challenges for programmed cell death 1 (PD-1)/PD-1 ligand (PD-L1) checkpoint
blockade lie in a lack of sufficient T cell infiltration, tumor immunosuppressive …
blockade lie in a lack of sufficient T cell infiltration, tumor immunosuppressive …
Exosomes as new generation vehicles for drug delivery: biomedical applications and future perspectives
A Rajput, A Varshney, R Bajaj, V Pokharkar - Molecules, 2022 - mdpi.com
Currently, particular interest among the scientific community is focused on exploring the use
of exosomes for several pharmaceutical and biomedical applications. This is due to the …
of exosomes for several pharmaceutical and biomedical applications. This is due to the …
[HTML][HTML] New advances in exosome-based targeted drug delivery systems
D Ferreira, JN Moreira, LR Rodrigues - Critical Reviews in Oncology …, 2022 - Elsevier
In recent years, various drug nano-delivery platforms have emerged to enhance drug
effectiveness in cancer treatment. However, their successful translation to clinics have been …
effectiveness in cancer treatment. However, their successful translation to clinics have been …
Tumor-derived extracellular vesicles: The metastatic organotropism drivers
The continuous growing, spreading, and metastasis of tumor cells depend on intercellular
communication within cells resident in a tissue environment. Such communication is …
communication within cells resident in a tissue environment. Such communication is …
The role of microRNAs in the pathophysiology of human central nervous system: a focus on neurodegenerative diseases
Abstract microRNAs (miRNAs) are suggested to play substantial roles in regulating the
development and various physiologic functions of the central nervous system (CNS). These …
development and various physiologic functions of the central nervous system (CNS). These …
Promising applications of tumor spheroids and organoids for personalized medicine
Simple Summary Presently, the investigation of the tumor is carried out using different
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
[HTML][HTML] Small extracellular vesicles in cancer
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
Cell Culture Based in vitro Test Systems for Anticancer Drug Screening
The development of new high-tech systems for screening anticancer drugs is one of the
main problems of preclinical screening. Poor correlation between preclinical in vitro and in …
main problems of preclinical screening. Poor correlation between preclinical in vitro and in …