Ribosomal proteins are ubiquitous, abundant, and RNA binding: prime candidates for
recruitment to extraribosomal functions. Indeed, they participate in balancing the synthesis of …

Aminoacylation of transfer RNAs establishes the rules of the genetic code. The reactions are
catalyzed by an ancient group of 20 enzymes (one for each amino acid) known as …

Mammalian tissues engage in specialized physiology that is regulated through reversible
modification of protein cysteine residues by reactive oxygen species (ROS). ROS regulate a …

Dysfunctions in mitochondria–the powerhouses of the cell–lead to several human
pathologies. Because mitochondria integrate nuclear and mitochondrial genetic systems …

Proteins are likely to organize into complexes that assemble and disassemble depending on
cellular needs. When≈ 800 yeast strains expressing GFP-tagged proteins were grown to …

Over the past decade, the identification of cancer-associated factors has been a subject of
primary interest not only for understanding the basic mechanisms of tumorigenesis but also …

Processing bodies (PBs) and Stress Granules (SGs) are the founding members of a new
class of RNA granules, known as mRNA silencing foci, as they harbour transcripts …

Functionally related genes are coregulated by specific RNA–protein interactions that direct
transcript-selective translational control. In myeloid cells, interferon (IFN)-γ induces formation …

The aminoacyl‐tRNA synthetases are prominently known for their classic function in the first
step of protein synthesis, where they bear the responsibility of setting the genetic code. Each …

Known as an essential component of the translational apparatus, the aminoacyl-tRNA
synthetase family catalyzes the first step reaction in protein synthesis, that is, to specifically …