Exercise has been shown to benefit brain structure and function, particularly in aging
populations. However, the mechanisms by which exercise exerts its effects, especially in …

Numbers of overweight and obese individuals are increasing in the United States and
globally, and, correspondingly, the associated health care costs are rising dramatically …

Hippocampal volume is a marker of brain health and is reduced with aging and neurological
disease. Exercise may be effective at increasing and preserving hippocampal volume …

Over the last two decades, numerous human MRI studies of neuroplasticity have shown
compelling evidence for extensive and rapid experience-induced brain plasticity in vivo. To …

There is growing evidence that exercise induced experience dependent plasticity may foster
structural and functional recovery following brain injury. We examined the efficacy of …

Plasticity can be defined as the brain's capacity to achieve lasting structural changes in
response to environmental demands that are not fully met by the organism's current …

Endurance exercise improves cardiovascular and musculoskeletal function and may also
increase the information processing capacities of the brain. Animal and human research …

Schizophrenia is a severe neuropsychiatric disease that is associated with neurobiological
alterations in multiple brain regions and peripheral organs. Negative symptoms and …

An organizational pattern seen in the brain, termed structural covariance, is the statistical
association of pairs of brain regions in their anatomical properties. These associations …

Atrophy has become a clinically relevant marker of progressive neurodegeneration in
multiple sclerosis (MS). To better understand atrophy, mouse models that feature atrophy …