Simvastatin affects Nrf2/MAPK signaling pathway and hepatic histological structure change in Gambusia affinis

S Bao, J Lin, M Xie, C Wang, X Nie - Chemosphere, 2021 - Elsevier
Simvastatin (SV) is a typical lipid-lowering agent detected widely in waters, so its latent toxic
effects to fish are deserved of concern. The purposes of this study aim at revealing the …

[HTML][HTML] Endocrine Disruption of Propylparaben in the Male Mosquitofish (Gambusia affinis): Tissue Injuries and Abnormal Gene Expressions of Hypothalamic …

Y Ma, Y Li, X Song, T Yang, H Wang, Y Liang… - International Journal of …, 2023 - mdpi.com
Propylparaben (PrP) is a widely used preservative that is constantly detected in aquatic
environments and poses a potential threat to aquatic ecosystems. In the present work, adult …

Response of PXR signaling pathway to simvastatin exposure in mosquitofish (Gambusia affinis) and its histological changes

S Bao, X Nie, Y Liu, C Wang, S Liu - Ecotoxicology and environmental …, 2018 - Elsevier
As a widely used lipid lowering agent, simvastatin recently has been frequently detected in
aquatic environment and the potential adverse effects from simvastatin exposure to non …

Diclofenac exposure alter the expression of PXR and its downstream target genes in mosquito fish (Gambusia affinis)

S Bao, X Nie, Y Liu, C Wang, W Li, S Liu - Science of the Total Environment, 2018 - Elsevier
As one of widely used drugs, Diclofenac (DCF) recently has been universally detected in
aquatic environment and some negative effects derived from DCF exposure to mammals …

2 种抗生素联合暴露对食蚊鱼抗氧化酶活力及相关基因表达的影响.

黎昕, 宋晓红, 李钰静, 杨涛, 闫小雨… - Asian Journals of …, 2022 - search.ebscohost.com
水环境中存在多种抗生素残留, 其造成的联合毒性对生物链产生不可忽视的影响.
本研究采用氧氟沙星(ofloxacin, OFL) 和磺胺甲恶唑(sulfamethoxazole, SMX) …

OFL 和SMX 单一及复合胁迫对食蚊鱼仔鱼的毒性影响.

杨涛, 黎昕, 马雲, 郭美莎, 宋晓红… - Environmental …, 2023 - search.ebscohost.com
抗生素在水环境中持续存在, 其单一与复合胁迫对水生生物的毒性效应可能具有不同特征.
该研究以典型抗生素氧氟沙星(OFL) 和磺胺甲恶唑(SMX) 为研究对象, 基于病理损伤(H&E 染色) …

3 种多环芳烃对海胆细胞色素CYP17A1 基因表达的影响.

刘帅, 宿甜甜, 刘长发, 魏海峰… - Asian Journals of …, 2020 - search.ebscohost.com
为揭示不同种类多环芳烃(PAHs) 污染物对中间球海胆(Strongylocentrotus intermedius)
的生态毒理效应, 研究了不同浓度的苯并(a) 芘(1, 5 和20 μg· L-1) 以及2 种烷基多环芳烃3 …

食蚊鱼P-糖蛋白基因克隆及三氯生对其mRNA 表达的影响.

宋晓红, 陆爱金, 杜士林, 陈双凤… - Asian Journals of …, 2020 - search.ebscohost.com
三氯生(TCS) 是一种广谱高效抗菌剂, 在水环境和生物体内均不同程度检出,
对水生生物具有潜在风险. P-糖蛋白(P-gp) 是生物体多型异源物质抗性防御系统中重要的“膜 …

[引用][C] 2 种烷基多环芳烃对仿刺参CYP450 和p53 基因表达的影响研究

李香, 魏海峰, 刘长发, 宋雪, 赵肖依, 赵雨朦, 夏宁… - Asian Journal of …, 2019

[引用][C] Cloning of P-Glycoprotein Gene and Effects of Triclosan on Its mRNA Expression in Mosquitofish (Gambusia affinis)

S Xiaohong, L Aijin, D Shilin… - Asian Journal of …, 2020 - Asian Journal of Ecotoxicology