The most commonly prescribed oral anticoagulants worldwide are the vitamin K antagonists
(VKAs) such as warfarin. Factors affecting the pharmacokinetics of VKAs are important …

Amiodarone is an iodinated benzofuran derivative, a highly lipophilic drug with
unpredictable pharmacokinetics. Although originally classified as a class III agent due to its …

Background New‐onset postoperative atrial fibrillation (poAF) complicates approximately 20‐
60% of all cardiac surgical procedures and is associated with an increased periprocedural …

A number of non‐cardiovascular drugs have been withdrawn from clinical use due to
unacceptable adverse cardiac side‐effects involving drug‐induced Torsades de Pointes …

Psychiatric and physical conditions often coexist, and there is robust evidence that
associates the frequency of depression with single and multiple physical conditions. More …

Lopinavir-ritonavir combination is being used for the treatment of SARS-CoV-2 infection. A
low dose of ritonavir is added to other protease inhibitors to take advantage of potent …

Much attention recently has focused on drugs that prolong the QT interval, potentially
leading to fatal cardiac dysrhythmias (eg, torsade de pointes). We provide a detailed review …

Arrhythmia is one of the commonly heart diseases with observed abnormal heart-beat
rhythm that caused by the obstacles of cardiac activity and conduction. The arrhythmic …

A great many cardiovascular drugs (CVDs) have the potential to induce adverse reactions in
the mouth. The prevalence of such reactions is not known, however, since many are …

Adrenergic β-blockers are used to treat many conditions, including hypertension, cardiac
arrhythmias, heart failure, angina pectoris, migraine, and tremors. The majority of the β …