The drug delivery system enables the release of the active pharmaceutical ingredient to
achieve a desired therapeutic response. Conventional drug delivery systems (tablets …

RNA interference mediated by small interfering RNAs (siRNAs) has been exploited for the
development of therapeutics. siRNAs can be a powerful therapeutic tool because the …

The transdermal route of administration provides numerous advantages over conventional
routes ie, oral or injectable for the treatment of different diseases and cosmetics applications …

Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a
global burden and affecting the world economy. Skin diseases severely impact the patients' …

Abstract P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX)
resistance. In this review, we highlight the molecular avenues regulating P-gp, such as Nrf2 …

Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …

Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Hydrogels are hydrophilic polymer networks, able to absorb large amount of water,
increasing their volume and showing a plethora of different material behaviors. Since their …

Chronic, non-healing wounds place a significant burden on patients and healthcare
systems, resulting in impaired mobility, limb amputation, or even death. Chronic wounds …

Introduction: Transdermal drug delivery has several clinical benefits over conventional
routes of drug administration. To open the transdermal route for a wider range of drugs …