The synthesis and trafficking of iron-sulfur (Fe-S) clusters in both prokaryotes and
eukaryotes requires coordination within an expanding network of proteins that function in the …

Fungal infections continue to represent a major threat to public health, particularly with the
emergence of multidrug-resistant fungal pathogens. As part of the innate immune response …

Plant pathogens are challenged by host-derived iron starvation or excess during infection,
but the mechanism through which pathogens counteract iron stress is unclear. Here, we …

Iron acquisition is critical for pathogens to proliferate during invasive infection, and the
human fungal pathogen Candida albicans is no exception. The iron regulatory network …

Monothiol glutaredoxins are important regulators of iron homeostasis that play conserved
roles in the sensing and trafficking of iron-sulfur clusters. We previously characterized the …

Non-proteinogenic neurotoxic amino acid β-N-methylamino-L-alanine (BMAA) is
synthesized by cyanobacteria, diatoms, and dinoflagellates, and is known to be a causative …

Iron acquisition is critical for pathogenic fungi to adapt to and survive within the host
environment. However, to same extent, the fungi must also avoid the detrimental effects …

The corn smut fungus, Ustilago maydis, is an excellent model for studying biotrophic plant-
pathogen interactions, including nutritional adaptation to the host environment. Iron …

Due to iron's essential role in cellular metabolism, most organisms must maintain their
homeostasis. In this regard, the fission yeast Schizosaccharomyces pombe (sp) uses two …

Prevalence of fungal diseases has increased globally in recent years, which often
associated with increased immunocompromised patients, aging populations, and the novel …