The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

Screening cell–cell communication in spatial transcriptomics via collective optimal transport

Z Cang, Y Zhao, AA Almet, A Stabell, R Ramos… - Nature …, 2023 - nature.com
Spatial transcriptomic technologies and spatially annotated single-cell RNA sequencing
datasets provide unprecedented opportunities to dissect cell–cell communication (CCC) …

Neurobiology of the lateral septum: regulation of social behavior

R Menon, T Süß, VE de Moura Oliveira… - Trends in …, 2022 - cell.com
Social interactions are essential for mammalian life and are regulated by evolutionary
conserved neuronal mechanisms. An individual's internal state, experiences, and the nature …

Social circuits and their dysfunction in autism spectrum disorder

M Sato, N Nakai, S Fujima, KY Choe, T Takumi - Molecular Psychiatry, 2023 - nature.com
Social behaviors, how individuals act cooperatively and competitively with conspecifics, are
widely seen across species. Rodents display various social behaviors, and many different …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

Neural circuits regulating prosocial behaviors

JJ Walsh, DJ Christoffel, RC Malenka - Neuropsychopharmacology, 2023 - nature.com
Positive, prosocial interactions are essential for survival, development, and well-being.
These intricate and complex behaviors are mediated by an amalgamation of neural circuit …

Therapeutic mechanisms of psychedelics and entactogens

BD Heifets, DE Olson - Neuropsychopharmacology, 2024 - nature.com
Recent clinical and preclinical evidence suggests that psychedelics and entactogens may
produce both rapid and sustained therapeutic effects across several indications. Currently …

Refining oxytocin therapy for autism: context is key

CL Ford, LJ Young - Nature Reviews Neurology, 2022 - nature.com
A recent clinical trial found no effect of chronic intranasal oxytocin on social behaviour in
children with autism spectrum disorders. The result is not surprising, as oxytocin facilitates …

Oxytocin-based therapies for treatment of Prader-Willi and Schaaf-Yang syndromes: evidence, disappointments, and future research strategies

F Althammer, F Muscatelli, V Grinevich… - Translational …, 2022 - nature.com
The prosocial neuropeptide oxytocin is being developed as a potential treatment for various
neuropsychiatric disorders including autism spectrum disorder (ASD). Early studies using …