Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Simple Summary Despite clinical success, only a limited percentage of cancer patients are
responsive to immunotherapy. Recently, gut microbiota modulation has been suggested as …

Previous studies noted an imbalance in T helper (Th) 17 and regulatory T cells (Tregs) in
experimental autoimmune encephalomyelitis (EAE), a multiple sclerosis animal model …

Multiple sclerosis (MS) is a complex inflammatory and demyelinating disease of the central
nervous system (CNS) frequently starts in young adulthood. Demyelination, inflammatory …

As a cellular bulk degradation and survival mechanism, autophagy is implicated in diverse
biological processes. Genome-wide association studies have revealed the link between …

Multiple sclerosis is an autoimmune treatable but not curable disease. There are a
multiplicity of medications for multiple sclerosis therapy, including a class entitled disease …

Vitamin D is known to have immunomodulatory properties and its deficiency is identified as
an environmental risk factor for the development of autoimmune diseases, including multiple …

Oligodendrocytes not only produce myelin to facilitate nerve impulse conduction, but are
also essential metabolic partners of the axon. Oligodendrocyte loss and myelin destruction …

Background & aims In our previous study, a Seesaw model was proposed for the fluctuation
of crucial anti-(IL-10) and pro-inflammatory (Il-6 & IL-17A) cytokines through vitamin D3. In …

Background Although the exact mechanism involved in migraine pathogenesis remained
uncertain, and different researches have been developed to address the role of …