Thymoquinone enhanced the antitumor activity of cisplatin in human bladder cancer 5637 cells...

Natural products and derivatives in renal, urothelial and testicular cancers: targeting signaling pathways and therapeutic potential

D Li, J Wang, Z Tuo, KH Yoo, Q Yu, A Miyamoto… - Phytomedicine, 2024 - Elsevier
Background: Natural products have demonstrated significant potential in cancer drug
discovery, particularly in renal cancer (RCa), urothelial carcinoma (UC), and testicular …
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Tracing metabolic route of thymoquinone biosynthesis in diverse Nigella sativa L. cultivars using RP-HPLC technique

U Gyaneshwari, B Pandey - Industrial Crops and Products, 2024 - Elsevier
Although the therapeutic role of Nigella sativa has been known for a long time, for optimal
utilization of plant parts, the developmental profiling of bioactive constituents and their …
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The Effect of Thymoquinone on the TNF-α/OTULIN/NF-κB Axis Against Cisplatin-İnduced Testicular Tissue Damage

T Yalçın, S Kaya, A Yiğin, CA Ağca, D Özdemir… - Reproductive …, 2024 - Springer
One of the adverse effects of the antineoplastic drug cisplatin (CS) is damage to testicular
tissue. This study aimed to examine the potential therapeutic effect of thymoquinone (TQ), a …
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