Hemocompatibility challenge of membrane oxygenator for artificial lung technology
The artificial lung (AL) technology is one of the membrane-based artificial organs that partly
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …
The roles of membrane technology in artificial organs: current challenges and perspectives
The recent outbreak of the COVID-19 pandemic in 2020 reasserted the necessity of artificial
lung membrane technology to treat patients with acute lung failure. In addition, the aging …
lung membrane technology to treat patients with acute lung failure. In addition, the aging …
Transplantation, bridging, and support technologies in pulmonary hypertension
L Savale, A Benazzo, P Corris… - European …, 2024 - publications.ersnet.org
Despite the progress made in medical therapies for treating pulmonary hypertension (PH), a
subset of patients remain susceptible to developing a maladaptive right ventricular …
subset of patients remain susceptible to developing a maladaptive right ventricular …
In vitro models for thrombogenicity testing of blood-recirculating medical devices
DN Sarode, S Roy - Expert review of medical devices, 2019 - Taylor & Francis
Introduction: Blood-recirculating medical devices, such as mechanical circulatory support
(MCS), extracorporeal membrane oxygenators (ECMO), and hemodialyzers, are commonly …
(MCS), extracorporeal membrane oxygenators (ECMO), and hemodialyzers, are commonly …
In vivo 5 day animal studies of a compact, wearable pumping artificial lung
SP Madhani, BJ Frankowski, SH Ye, GW Burgreen… - ASAIO …, 2019 - journals.lww.com
Recent studies show improved outcomes in ambulated lung failure patients. Ambulation still
remains a challenge in these patients. This necessitates development of more compact and …
remains a challenge in these patients. This necessitates development of more compact and …
[HTML][HTML] A Wearable Extracorporeal CO2 Removal System with a Closed-Loop Feedback
A Zhang, BJ Haimowitz, K Tharwani, A Rojas-Peña… - Bioengineering, 2024 - mdpi.com
Extracorporeal Carbon Dioxide Removal (ECCO2R) systems support patients with severe
respiratory failure. Concurrent ambulation and physical therapy improve patient outcomes …
respiratory failure. Concurrent ambulation and physical therapy improve patient outcomes …
Shape design of an artificial pump-lung using high-resolution hemodynamic simulation with high-performance computing
Accurate and fast prediction of the hemodynamics of the artificial pump-lung is critical in the
design process. In this study, a comprehensive computational framework, including a sliding …
design process. In this study, a comprehensive computational framework, including a sliding …
Advances in extracorporeal membrane oxygenator design for artificial placenta technology
DG Blauvelt, EN Abada, P Oishi, S Roy - Artificial organs, 2021 - Wiley Online Library
Extreme prematurity, defined as a gestational age of fewer than 28 weeks, is a significant
health problem worldwide. It carries a high burden of mortality and morbidity, in large part …
health problem worldwide. It carries a high burden of mortality and morbidity, in large part …
Ambulatory 7-day mechanical circulatory support in sheep model of pulmonary hypertension and right heart failure
Background Right heart failure is the major cause of death in pulmonary hypertension. Lung
transplantation is the only long-term treatment option for patients who fail medical therapy …
transplantation is the only long-term treatment option for patients who fail medical therapy …
Bench Validation of a Compact Low-Flow CO2 Removal Device
AG May, RG Jeffries, BJ Frankowski… - Intensive care medicine …, 2018 - Springer
Background There is increasing evidence demonstrating the value of partial extracorporeal
CO 2 removal (ECCO 2 R) for the treatment of hypercapnia in patients with acute …
CO 2 removal (ECCO 2 R) for the treatment of hypercapnia in patients with acute …