Advances in the Computational Assessment of Disturbed Coronary Flow and Wall Shear Stress: A Contemporary Review

AA Ekmejian, HJ Carpenter, JL Ciofani… - Journal of the …, 2024 - ahajournals.org
Coronary artery blood flow is influenced by various factors including vessel geometry,
hemodynamic conditions, timing in the cardiac cycle, and rheological conditions. Multiple …

Endothelial response to the combined biomechanics of vessel stiffness and shear stress is regulated via Piezo1

A Lai, Y Zhou, P Thurgood, C Chheang… - … Applied Materials & …, 2023 - ACS Publications
How endothelial cells sense and respond to dynamic changes in their biophysical
surroundings as we age is not fully understood. Vascular stiffness is clearly a contributing …

Multiplexed fluidic circuit board for controlled perfusion of 3D blood vessels-on-a-chip

MNS de Graaf, A Vivas, DG Kasi, FE van den Hil… - Lab on a Chip, 2023 - pubs.rsc.org
Three-dimensional (3D) blood vessels-on-a-chip (VoC) models integrate the biological
complexity of vessel walls with dynamic microenvironmental cues, such as wall shear stress …

Chronic heart failure induces early defenestration of liver sinusoidal endothelial cells (LSECs) in mice

K Wojnar‐Lason, U Tyrankiewicz, A Kij… - Acta …, 2024 - Wiley Online Library
Aim Chronic heart failure (CHF) is often linked to liver malfunction and systemic endothelial
dysfunction. However, whether cardio‐hepatic interactions in heart failure involve …

Global tendencies and frontier topics in hemodynamics research of intracranial aneurysms: a bibliometric analysis from 1999 to 2022

B Chen, S Huang, L Zhang, L Yang, Y Liu… - Frontiers in Physiology, 2023 - frontiersin.org
Background: Hemodynamics plays a crucial role in the initiation, enlargement, and rupture
of intracranial aneurysms (IAs). This bibliometric analysis aimed to map the knowledge …

[HTML][HTML] Bayesian network analysis reveals the interplay of intracranial aneurysm rupture risk factors

M Delucchi, GR Spinner, M Scutari, P Bijlenga… - Computers in Biology …, 2022 - Elsevier
Clinical decision making regarding the treatment of unruptured intracranial aneurysms (IA)
benefits from a better understanding of the interplay of IA rupture risk factors. Probabilistic …

Oral bacterial genic expression detection in aneurysm wall of a French population sample–preliminary monocentric study

A Devalckeneer, T Lu, P Bourgeois, CA Maurage… - Neurosurgical …, 2024 - Springer
Introduction The etiology of brain aneurysms remains poorly understood. Finnish research
suggests that oral bacteria might contribute to the development and rupture of brain …

Effect of blood transfusion on cerebral hemodynamics and vascular topology described by computational fluid dynamics in sickle cell disease patients

RP Sawyer, S Pun, KA Karkoska, CA Clendinen… - Brain Sciences, 2022 - mdpi.com
The main objective of this study was to demonstrate that computational fluid dynamics (CFD)
modeling can be used to study the contribution of covert and overt vascular architecture to …

Nonlinear Biomechanical Behaviour of Extracranial Carotid Artery Aneurysms in the Framework of Windkessel Effect via FSI Technique

K Moghadasi, MH Ghayesh, J Li, E Hu… - Journal of the …, 2024 - Elsevier
Extracranial carotid artery aneurysms (ECCA) lead to rupture and neurologic symptoms from
embolisation, with potentially fatal outcomes. Investigating the biomechanical behaviour of …

The biomechanical effects of different membrane layer structures and material constitutive modeling on patient-specific cerebral aneurysms

X Fan, A Zhang, Q Zheng, P Li, Y Wang… - … in Bioengineering and …, 2024 - frontiersin.org
The prevention, control and treatment of cerebral aneurysm (CA) has become a common
concern of human society, and by simulating the biomechanical environment of CA using …