Breakthroughs in hepatitis C research: from discovery to cure

MP Manns, B Maasoumy - Nature reviews Gastroenterology & …, 2022 - nature.com
In the 1970s, an unknown virus was suspected for documented cases of transfusion-
associated hepatitis, a phenomenon called non-A, non-B hepatitis. In 1989, the infectious …

EASL clinical practice guidelines: management of hepatocellular carcinoma

PR Galle, A Forner, JM Llovet, V Mazzaferro… - Journal of …, 2018 - Elsevier
Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …

EASL recommendations on treatment of hepatitis C: final update of the series☆

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2020 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

EASL recommendations on treatment of hepatitis C 2016

European Association for The Study of The Liver - Journal of hepatology, 2017 - Elsevier
Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease
worldwide [1]. The long-term impact of HCV infection is highly variable, ranging from minimal …

Unexpected high rate of early tumor recurrence in patients with HCV-related HCC undergoing interferon-free therapy

M Reig, Z Mariño, C Perelló, M Iñarrairaegui… - Journal of …, 2016 - Elsevier
Background & Aims The success of direct-acting antivirals (DAA) against hepatitis C is a
major breakthrough in hepatology. Until now, however, there are very few data on the effect …

Hepatocellular carcinoma risk following direct-acting antiviral HCV therapy: a systematic review, meta-analyses, and meta-regression

R Waziry, B Hajarizadeh, J Grebely, J Amin, M Law… - Journal of …, 2017 - Elsevier
Background & Aims The risk of hepatocellular carcinoma (HCC) occurrence or recurrence
following direct-acting antiviral (DAA) hepatitis C virus (HCV) therapy remains unclear. The …

EASL recommendations on treatment of hepatitis C 2018

JM Pawlotsky, F Negro, A Aghemo, M Berenguer… - Journal of …, 2018 - Elsevier
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with
approximately 71 million chronically infected individuals worldwide. Clinical care for patients …

Outcomes after successful direct-acting antiviral therapy for patients with chronic hepatitis C and decompensated cirrhosis

MCM Cheung, AJ Walker, BE Hudson, S Verma… - Journal of …, 2016 - Elsevier
Background & Aims Direct-acting antivirals have become widely used for patients with
chronic hepatitis C virus infection with decompensated cirrhosis. Virological responses are …

[PDF][PDF] Projections of primary liver cancer to 2030 in 30 countries worldwide

PC Valery, M Laversanne, PJ Clark, JL Petrick… - …, 2018 - Wiley Online Library
Primary liver cancer (PLC) is the sixth most common cancer worldwide and the second most
common cause of cancer death. Future predictions can inform health planners and raise …

Quantitative elastography methods in liver disease: current evidence and future directions

P Kennedy, M Wagner, L Castéra, CW Hong… - Radiology, 2018 - pubs.rsna.org
Chronic liver diseases often result in the development of liver fibrosis and ultimately,
cirrhosis. Treatment strategies and prognosis differ greatly depending on the severity of liver …