Oral candidiasis: A disease of opportunity

T Vila, AS Sultan, D Montelongo-Jauregui… - Journal of fungi, 2020 - mdpi.com
Oral candidiasis, commonly referred to as “thrush,” is an opportunistic fungal infection that
commonly affects the oral mucosa. The main causative agent, Candida albicans, is a highly …

The power of saliva: Antimicrobial and beyond

T Vila, AM Rizk, AS Sultan, MA Jabra-Rizk - PLoS pathogens, 2019 - journals.plos.org
The oral cavity is a major portal of entry for pathogens that may lead to changes in the
normal microflora [1]. The homeostasis of the oral cavity is maintained by saliva, an …

Candida albicans biofilm development is governed by cooperative attachment and adhesion maintenance proteins

AD McCall, RU Pathirana, A Prabhakar… - NPJ biofilms and …, 2019 - nature.com
The opportunistic fungal pathogen Candida albicans is capable of adhering to the oral
mucosa despite forces created by salivary flow. Although many fungal adhesion proteins …

PANoptosis: a new insight into oral infectious diseases

W Jiang, Z Deng, X Dai, W Zhao - Frontiers in immunology, 2021 - frontiersin.org
The oral microbiome, one of the most complex and intensive microbial ecosystems in the
human body, comprises bacteria, archaea, fungi, protozoa, and viruses. Dysbiosis of the oral …

Targeting Candida albicans filamentation for antifungal drug development

T Vila, JA Romo, CG Pierce, SF McHardy, SP Saville… - Virulence, 2017 - Taylor & Francis
Candida albicans remains the main etiological agent of candidiasis, as this otherwise
normal commensal of humans is capable of causing active infection in immune-and …

EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans

M Swidergall, NV Solis, MS Lionakis, SG Filler - Nature microbiology, 2018 - nature.com
Oral epithelial cells discriminate between pathogenic and non-pathogenic stimuli, and only
induce an inflammatory response when they are exposed to high levels of a potentially …

Green synthesis, antimicrobial, antibiofilm and antitumor activities of superparamagnetic γ-Fe2O3 NPs and their molecular docking study with cell wall mannoproteins …

MA Ansari, SMM Asiri - International Journal of Biological Macromolecules, 2021 - Elsevier
Fatty acids-assisted superparamagnetic maghemite (γ-Fe 2 O 3) NPs was biologically
synthesized using extract of polyherbal drug Liv52 (L52E). The NPs were characterized by …

IκBζ is an essential mediator of immunity to oropharyngeal candidiasis

TC Taylor, BM Coleman, SP Arunkumar, I Dey… - Cell Host & Microbe, 2023 - cell.com
Fungal infections are a global threat; yet, there are no licensed vaccines to any fungal
pathogens. Th17 cells mediate immunity to Candida albicans, particularly oropharyngeal …

Action mechanisms of probiotics on Candida spp. and candidiasis prevention: an update

FC Ribeiro, RD Rossoni, PP De Barros… - Journal of applied …, 2020 - academic.oup.com
Due to the high incidence of fungal infections caused by Candida species and their
increasing resistance to antimicrobial treatments, alternative therapies such as probiotics …

miRNA‐encapsulated abiotic materials and biovectors for cutaneous and oral wound healing: biogenesis, mechanisms, and delivery nanocarriers

A Deka Dey, S Yousefiasl, A Kumar… - Bioengineering & …, 2023 - Wiley Online Library
MicroRNAs (miRNAs) as therapeutic agents have attracted increasing interest in the past
decade owing to their significant effectiveness in treating a wide array of ailments. These …