The epithelial sodium channel (ENaC) is a heterotrimer and is widely distributed throughout
the kidneys, blood vessels, lungs, colons, and many other organs. The basic role of the …

Diarylamidines are a group of widely used small molecule drugs. One common use of
diarylamidines is their pharmacological inhibition of ligand-gated cation channels, including …

Rapid signaling between neurons is mediated by ligand-gated ion channels, cell-surface
proteins with an extracellular ligand-binding domain and a membrane-spanning ion channel …

The nematode Caenorhabditis elegans is among the most intensely studied animals in
modern experimental biology. Its amenability to classical and molecular genetics, compact …

Ion channels are necessary for proper water and nutrient absorption in the intestine, which
supports cellular metabolism and organismal growth. While a role for Na+ co-transporters …

Ion channels and transporters keep ideas flowing Page 1 This is an Accepted Article that has
been peer-reviewed and approved for publication in the The Journal of Physiology, but has yet …

Recent studies reveal the gut-brain axis, with its bidirectional signaling function, plays a
crucial role in host physiological regulation. Through the gut-to-brain signaling, the nervous …

Recent studies reveal the gut-brain axis, with its bidirectional signaling function, plays a
crucial role in host physiological regulation. Through the gut-to-brain signaling, the nervous …

抄録 Cell membranes hold an array of receptors and sensors to perceive environmental
cues and translate them into intracellular signals. Lipid components play a crucial role …