[HTML][HTML] Superoxide dismutase administration: A review of proposed human uses

AC Rosa, D Corsi, N Cavi, N Bruni, F Dosio - Molecules, 2021 - mdpi.com
Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

[HTML][HTML] Rebalancing NOX2/Nrf2 to limit inflammation and oxidative stress across gut-brain axis in migraine

A Ardizzone, AP Capra, A Repici, M Lanza… - Free Radical Biology …, 2024 - Elsevier
Migraine is one of the most common neurological illnesses, and it is characterized by
complicated neurobiology. It was confirmed the influence of inflammation and oxidative …

Cigarette smoke induces epithelial-to-mesenchymal transition, stemness, and metastasis in lung adenocarcinoma cells via upregulated RUNX-2/galectin-3 pathway

JR Sharma, H Agraval, UCS Yadav - Life Sciences, 2023 - Elsevier
Aims An elevated level of galectin-3, a carbohydrate-binding lectin implicated in
tumorigenesis, metastasis, and epithelial-mesenchymal transition (EMT), has been found in …

Effect of cyclosporine A-tempol topical gel for the treatment of alopecia and anti-inflammatory disorders

S Palakkal, A Cortial, M Frušić-Zlotkin, Y Soroka… - International Journal of …, 2023 - Elsevier
Over the years, extensive research has been carried out to develop new chemical entities for
hair loss treatment. Despite these efforts, the newly developed topical and oral treatments …

[HTML][HTML] The Role of the Nrf2 Pathway in Airway Tissue Damage Due to Viral Respiratory Infections

AJ Kombe Kombe, L Fotoohabadi, R Nanduri… - International journal of …, 2024 - mdpi.com
Respiratory viruses constitute a significant cause of illness and death worldwide.
Respiratory virus-associated injuries include oxidative stress, ferroptosis, inflammation …

Renal arterial infusion of tempol prevents medullary hypoperfusion, hypoxia, and acute kidney injury in ovine gram‐negative sepsis

AH Betrie, S Ma, CPC Ow, RM Peiris… - Acta …, 2023 - Wiley Online Library
Aim Renal medullary hypoperfusion and hypoxia precede acute kidney injury (AKI) in ovine
sepsis. Oxidative/nitrosative stress, inflammation, and impaired nitric oxide generation may …

[HTML][HTML] Tempol improves optic nerve histopathology and ultrastructures in cisplatin-induced optic neuropathy in rats by targeting oxidative stress—Endoplasmic …

AE Alsemeh, MAE Hulail, HEL Mokhtar… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Optic neuropathy is an affection of the optic neurons, which ends with blindness
and occurs either primarily due to direct affection of the optic nerve or secondarily as a …

[HTML][HTML] Antimicrobial photodynamic therapy (aPDT) with curcumin controls intradermal infection by Staphylococcus aureus in mice with type 1 diabetes mellitus: a …

IPR Muniz, MPL Galantini, IS Ribeiro… - … of Photochemistry and …, 2021 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the main pathogens that cause
infections in diabetic individuals. In this paper, we report the outcomes of our investigation …

[HTML][HTML] Beneficial effect of tempol, a membrane-permeable radical scavenger, on inflammation and osteoarthritis in in vitro models

G Calabrese, A Ardizzone, M Campolo, S Conoci… - Biomolecules, 2021 - mdpi.com
Osteoarthritis (OA) is one of the most common and widespread diseases which is highly
disabling for humans. This makes OA a chronic disease for which it is urgent to find new …

[HTML][HTML] Tempol differently affects cellular redox changes and antioxidant enzymes in various lung-related cells

WH Park - Scientific Reports, 2021 - nature.com
Abstract Tempol (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine-1-oxyl) is a potential redox agent
in cells. The present study investigated changes in cellular reactive oxygen species (ROS) …