Lipid metabolite biomarkers in cardiovascular disease: Discovery and biomechanism translation from human studies

P McGranaghan, JA Kirwan, MA Garcia-Rivera… - Metabolites, 2021 - mdpi.com
Lipids represent a valuable target for metabolomic studies since altered lipid metabolism is
known to drive the pathological changes in cardiovascular disease (CVD). Metabolomic …

Lipid‐induced mechanisms of metabolic syndrome

YK Denisenko, OY Kytikova… - Journal of …, 2020 - Wiley Online Library
Metabolic syndrome (MetS) has a worldwide tendency to increase and depends on many
components, which explains the complexity of diagnosis, approaches to the prevention, and …

Normal weight obese (NWO) women: an evaluation of a candidate new syndrome

A De Lorenzo, R Martinoli, F Vaia… - Nutrition, Metabolism and …, 2006 - Elsevier
BACKGROUND AND AIMS: Obesity, an independent risk factor for cardiovascular disease
(CVD), has been associated with the early development of coronary atherosclerosis in …

Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease

Y Eguchi, T Eguchi, T Mizuta, Y Ide, T Yasutake… - Journal of …, 2006 - Springer
Background Nonalcoholic fatty liver diseases are often associated with obesity, insulin
resistance, and excessive visceral fat accumulation. The aims of this study were (1) to …

Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men

E Warensjö, U Risérus, B Vessby - Diabetologia, 2005 - Springer
Aims/hypothesis Types of dietary fat have been related to components of the metabolic
syndrome. Serum fatty acid composition mainly reflects dietary fat intake, but also …

[HTML][HTML] Plasma fatty acid composition is associated with the metabolic syndrome and low-grade inflammation in overweight adolescents

C Klein-Platat, J Drai, M Oujaa, JL Schlienger… - The American journal of …, 2005 - Elsevier
Background: Together with adiposity, plasma fatty acid (FA) composition can modulate the
development of the metabolic syndrome (MS). Objective: Our aim was to investigate the …

Comparison of lipid and fatty acid composition of the liver, subcutaneous and intra‐abdominal adipose tissue, and serum

A Kotronen, T Seppänen‐Laakso, J Westerbacka… - …, 2010 - Wiley Online Library
Ceramides may mediate saturated fat–induced insulin resistance, but there are no data
comparing ceramide concentrations between human tissues. We therefore performed …

Serum saturated fatty acids containing triacylglycerols are better markers of insulin resistance than total serum triacylglycerol concentrations

A Kotronen, VR Velagapudi, L Yetukuri, J Westerbacka… - Diabetologia, 2009 - Springer
Aims/hypothesis The weak relationship between insulin resistance and total serum
triacylglycerols (TGs) could be in part due to heterogeneity of TG molecules and their …

[HTML][HTML] Dietary Fats and the Gut Microbiota: Their impacts on lipid-induced metabolic syndrome

S Basak, A Banerjee, S Pathak, AK Duttaroy - Journal of Functional Foods, 2022 - Elsevier
The metabolic syndrome (MetS) produces low-grade inflammation, endothelial dysfunction,
platelet hyperactivity, oxidative stress and ultimately contributes to cardiovascular disease …

Alterations in plasma and tissue lipids associated with obesity and metabolic syndrome

CM Aguilera, M Gil-Campos, R Canete, A Gil - Clinical science, 2008 - portlandpress.com
The MS (metabolic syndrome) is a cluster of clinical and biochemical abnormalities
characterized by central obesity, dyslipidaemia [hypertriglyceridaemia and decreased HDL …