mGluR7 allosteric modulator AMN082 corrects protein synthesis and pathological phenotypes in FXS
Fragile X syndrome (FXS) is the leading cause of inherited autism and intellectual
disabilities. Aberrant protein synthesis due to the loss of fragile X messenger …
disabilities. Aberrant protein synthesis due to the loss of fragile X messenger …
Neural Hyperactivity Is a Core Pathophysiological Change Induced by Deletion of a High Autism Risk Gene Ash1L in the Mouse Brain
ASH1L is one of the highest risk genes associated with autism spectrum disorder (ASD) and
intellectual disability (ID). Our recent studies demonstrate that loss of Ash1l in the mouse …
intellectual disability (ID). Our recent studies demonstrate that loss of Ash1l in the mouse …
[PDF][PDF] FMR1 and Autism, an Intriguing Connection Revisited. Genes 2021, 12, 1218
Autism Spectrum Disorder (ASD) represents a distinct phenotype of behavioral dysfunction
that includes deficiencies in communication and stereotypic behaviors. ASD affects about …
that includes deficiencies in communication and stereotypic behaviors. ASD affects about …