The mechanical control of nervous system development

K Franze - Development, 2013 - journals.biologists.com
The development of the nervous system has so far, to a large extent, been considered in the
context of biochemistry, molecular biology and genetics. However, there is growing …

A quantitative overview of biophysical forces impinging on neural function

JK Mueller, WJ Tyler - Physical biology, 2014 - iopscience.iop.org
The fundamentals of neuronal membrane excitability are globally described using the
Hodgkin-Huxley (HH) model. The HH model, however, does not account for a number of …

A new framework for investigating the biological basis of degenerative cervical myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: mechanical stress …

BM Davies, O Mowforth, AA Gharooni… - Global Spine …, 2022 - journals.sagepub.com
Study Design Literature Review (Narrative) Objective To propose a new framework, to
support the investigation and understanding of the pathobiology of DCM, AO Spine …

Stretchable synaptic transistors with tunable synaptic behavior

X Wang, Y Yan, E Li, Y Liu, D Lai, Z Lin, Y Liu, H Chen… - Nano Energy, 2020 - Elsevier
Stretchable synaptic transistors (SSTs) are of paramount importance for the development of
soft machines and neuromorphic systems. Unfortunately, the reports about SSTs are very …

Synapses without tension fail to fire in an in vitro network of hippocampal neurons

MSH Joy, DL Nall, B Emon, KY Lee… - Proceedings of the …, 2023 - National Acad Sciences
Neurons in the brain communicate with each other at their synapses. It has long been
understood that this communication occurs through biochemical processes. Here, we reveal …

Coupled circumferential and axial tension driven by actin and myosin influences in vivo axon diameter

A Fan, A Tofangchi, M Kandel, G Popescu, T Saif - Scientific reports, 2017 - nature.com
It has long been known that neuronal axons are contractile. They actively maintain rest
tension along the longitudinal direction both in vitro and in vivo. Here we show evidence that …

Endocytosis and exocytosis protect cells against severe membrane tension variations

F Mao, Y Yang, H Jiang - Biophysical Journal, 2021 - cell.com
The ability of cells to regulate their shape and volume is critical for many cell functions. How
endocytosis and exocytosis, as important ways of membrane trafficking, affect cellular …

[HTML][HTML] Force: A messenger of axon outgrowth

V Raffa - Seminars in Cell & Developmental Biology, 2023 - Elsevier
The axon is a sophisticated macromolecular machine composed of interrelated parts that
transmit signals like spur gears transfer motion between parallel shafts. The growth cone is a …

On the Teneurin track: a new synaptic organization molecule emerges

TJ Mosca - Frontiers in cellular neuroscience, 2015 - frontiersin.org
To achieve proper synaptic development and function, coordinated signals must pass
between the pre-and postsynaptic membranes. Such transsynaptic signals can be …

Proteomic and functional analyses of the periodic membrane skeleton in neurons

R Zhou, B Han, R Nowak, Y Lu, E Heller, C Xia… - Nature …, 2022 - nature.com
Actin, spectrin, and associated molecules form a membrane-associated periodic skeleton
(MPS) in neurons. The molecular composition and functions of the MPS remain incompletely …