Role of interleukin-6 in cancer progression and therapeutic resistance
In the last several decades, the number of people dying from cancer-related deaths has not
reduced significantly despite phenomenal advances in the technologies related to diagnosis …
reduced significantly despite phenomenal advances in the technologies related to diagnosis …
[HTML][HTML] Chronic hyperglycemia mediated physiological alteration and metabolic distortion leads to organ dysfunction, infection, cancer progression and other …
Chronic exposure of glucose rich environment creates several physiological and
pathophysiological changes. There are several pathways by which hyperglycemia …
pathophysiological changes. There are several pathways by which hyperglycemia …
The effect of short-term hyperglycemia on the innate immune system
Background Diabetes mellitus increases the susceptibility to infection by altering both the
innate and the adaptive immune systems. Hyperglycemia has been associated with adverse …
innate and the adaptive immune systems. Hyperglycemia has been associated with adverse …
Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways
K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …
population. Both experimental and clinical evidence suggest that diabetic subjects are …
The role of nutrition in asthma prevention and treatment
J Alwarith, H Kahleova, L Crosby, A Brooks… - Nutrition …, 2020 - academic.oup.com
Asthma is a chronic respiratory condition characterized by airway inflammation and
hyperreactivity. Prevalence has continued to rise in recent decades as Western dietary …
hyperreactivity. Prevalence has continued to rise in recent decades as Western dietary …
Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections
Diabetes has been recognized as an important risk factor for a variety of intracellular
bacterial infections, but research into the dysregulated immune mechanisms contributing to …
bacterial infections, but research into the dysregulated immune mechanisms contributing to …
Vitamin E, oxidative stress, and inflammation
▪ Abstract Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in
the Western world. Its incidence has also been increasing lately in developing countries …
the Western world. Its incidence has also been increasing lately in developing countries …
The role of protein kinase C activation and the vascular complications of diabetes
ND Evcimen, GL King - Pharmacological research, 2007 - Elsevier
Diabetes mellitus is a chronic disease caused by inherited and/or acquired deficiency in
production of insulin by the pancreas, and by resistance to insulin's effects. Such a …
production of insulin by the pancreas, and by resistance to insulin's effects. Such a …
High glucose induces toll-like receptor expression in human monocytes: mechanism of activation
OBJECTIVE—Hyperglycemia-induced inflammation is central in diabetes complications,
and monocytes are important in orchestrating these effects. Toll-like receptors (TLRs) play a …
and monocytes are important in orchestrating these effects. Toll-like receptors (TLRs) play a …
Hyperglycemia associated metabolic and molecular alterations in cancer risk, progression, treatment, and mortality
P Ramteke, A Deb, V Shepal, MK Bhat - Cancers, 2019 - mdpi.com
Cancer and diabetes are amongst the leading causes of deaths worldwide. There is an
alarming rise in cancer incidences and mortality, with approximately 18.1 million new cases …
alarming rise in cancer incidences and mortality, with approximately 18.1 million new cases …