With the emergence of novel technologies and ground breaking concepts in BBB basic
research in the past decades, the researchers' attention on the critical role of blood brain …

Abstract Perinatal hypoxic‐ischemic (HI)‐related brain injury is an important cause of
morbidity and long‐standing disability in newborns. The only currently approved therapeutic …

Bioengineering of tissues and organs has the potential to generate functional replacement
organs. However, achieving the full‐thickness vascularization that is required for long‐term …

Blood-brain barrier (BBB) disruption is associated with hypoxia-ischemia (HI) induced brain
injury and life-long neurological pathologies. Treatment options are limited. Recently, we …

Birth asphyxia is a significant global health problem, responsible for~ 1.2 million neonatal
deaths each year worldwide. Those who survive often suffer from a range of health issues …

Cerebral hypoxia or ischemia results in cell death and cerebral edema, as well as other
cellular reactions such as angiogenesis and the reestablishment of functional …

Chronic moderate hypoxia induces angiogenic adaptation in the brain, reflecting a
modulatory role for oxygen in determining cerebrovascular development. Chronic …

G protein-coupled estrogen receptor 1 (GPER-1) plays important roles in estrogen-mediated
neuroprotection. However, protective effects of GPER-1 on blood-brain barrier (BBB) after …

Near‐term acute hypoxia in utero can result in significant fetal brain injury, with some brain
regions more vulnerable than others. As mitochondrial dysfunction is an underlying feature …

The aim of this study was to investigate the effects of direct creatine infusion on fetal
systemic metabolic and cardiovascular responses to mild acute in utero hypoxia. Pregnant …