The astrochemical evolutionary traits of phospholipid membrane homochirality
Compartmentalization is crucial for the evolution of life. Present-day phospholipid
membranes exhibit a high level of complexity and species-dependent homochirality, the so …
membranes exhibit a high level of complexity and species-dependent homochirality, the so …
Molecular Recognition in Mechanochemistry: Insights from Solid‐State NMR Spectroscopy
C Quaranta, I d'Anciães Almeida Silva… - Angewandte …, 2024 - Wiley Online Library
Molecular‐recognition events are highly relevant in biology and chemistry. In the present
study, we investigated such processes in the solid state under mechanochemical conditions …
study, we investigated such processes in the solid state under mechanochemical conditions …
Coacervation for biomedical applications: innovations involving nucleic acids
K Mirlohi, WCB McTigue - Soft Matter, 2025 - pubs.rsc.org
Gene therapies, drug delivery systems, vaccines, and many other therapeutics, although
seeing breakthroughs over the past few decades, still suffer from poor stability …
seeing breakthroughs over the past few decades, still suffer from poor stability …
Chirality-induced avalanche magnetization of magnetite by an RNA precursor
Homochirality is a hallmark of life on Earth. To achieve and maintain homochirality within a
prebiotic network, the presence of an environmental factor acting as a chiral agent and …
prebiotic network, the presence of an environmental factor acting as a chiral agent and …
Non-classical Temperature Dependence of Chirality-Induced Magnetization and Its Implications for RNA's Homochirality
The single-handedness of biomolecules is a characteristic feature of life on Earth, yet
achieving and maintaining a homochiral prebiotic network is a significant challenge. In our …
achieving and maintaining a homochiral prebiotic network is a significant challenge. In our …
Timing and Likelihood of the Origin of Life Derived from Post-Impact Highly Reducing Atmospheres
NF Wogan, DC Catling, KJ Zahnle - Astrobiology, 2024 - liebertpub.com
Big impacts on the early Earth would have created highly reducing atmospheres that
generated molecules needed for the origin of life, such as nitriles. However, such impactors …
generated molecules needed for the origin of life, such as nitriles. However, such impactors …
Stabilization of Prebiotic Vesicles by Peptides Depends on Sequence and Chirality: A Mechanism for Selection of Protocell-Associated Peptides
Cells require oligonucleotides and polypeptides with specific, homochiral sequences to
perform essential functions, but it is unclear how such oligomers were selected from random …
perform essential functions, but it is unclear how such oligomers were selected from random …
Step‐by‐Step Towards Biological Homochirality–from Prebiotic Randomness To Perfect Asymmetry
I Mejdrova, E Węgrzyn, T Carell - Chemistry–An Asian Journal, 2025 - Wiley Online Library
The history of life's formation and the origin of its stereochemistry are nearly as multifaceted
as the life itself. In this review, we focus on analyzing the step‐by‐step path leading to what …
as the life itself. In this review, we focus on analyzing the step‐by‐step path leading to what …
Stereoselectivity of Aminoacyl-RNA Loop-closing Ligation
The origin of amino acid homochirality remains an unresolved question in the origin of life.
The requirement of enantiopure nucleotides for nonenzymatic RNA copying strongly …
The requirement of enantiopure nucleotides for nonenzymatic RNA copying strongly …
A Review on Unveiling the Secrets of Epitranscriptomics: RNA Modifications in Health and Diseases
A Jadhav, A Pawar - Micro Environer, 2023 - microenvironer.com
Advancements in epi transcriptomics have reshaped our understanding of RNA's intricate
roles in cellular processes and disease. This abstract provides insights into the emerging …
roles in cellular processes and disease. This abstract provides insights into the emerging …