Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

JK Karimy, BC Reeves, E Damisah, PQ Duy… - Nature Reviews …, 2020 - nature.com
Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …

A systematic review on the epidemiology of normal pressure hydrocephalus

V Zaccaria, I Bacigalupo, G Gervasi… - Acta Neurologica …, 2020 - Wiley Online Library
Background The aim of this systematic review is to gather all available studies reporting
prevalence and incidence rates of iNPH and to assess their methodological quality and …

Mechanical properties in the glioma microenvironment: emerging insights and theranostic opportunities

AG Bhargav, JS Domino, R Chamoun… - Frontiers in …, 2022 - frontiersin.org
Gliomas represent the most common malignant primary brain tumors, and a high-grade
subset of these tumors including glioblastoma are particularly refractory to current standard …

Inflammatory hydrocephalus

SM Robert, BC Reeves, A Marlier, PQ Duy… - Child's Nervous …, 2021 - Springer
Reparative inflammation is an important protective response that eliminates foreign
organisms, damaged cells, and physical irritants. However, inappropriately triggered or …

Engineering innovations in medicine and biology: Revolutionizing patient care through mechanical solutions

EG Hanna, K Younes, R Roufayel, M Khazaal… - Heliyon, 2024 - cell.com
The overlap between mechanical engineering and medicine is expanding more and more
over the years. Engineers are now using their expertise to design and create functional …

Differential DNA methylation of the genes for amyloid precursor protein, tau, and neurofilaments in human traumatic brain injury

S Abu Hamdeh, DM Ciuculete, D Sarkisyan… - Journal of …, 2021 - liebertpub.com
Traumatic brain injury (TBI) is an established risk factor for neurodegenerative disorders and
dementias. Epigenetic modifications, such as DNA methylation, may alter the expression of …

Structural and functional connectivity in hydrocephalus: a scoping review

I Peña Pino, E Fellows, RA McGovern, CC Chen… - Neurosurgical …, 2024 - Springer
Optimizing the treatment of hydrocephalus remains a major challenge in adult and pediatric
neurosurgery. Currently, clinical treatment relies heavily on anatomic imaging of ventricular …

Comparative durability and costs analysis of ventricular shunts

N Agarwal, A Kashkoush, MM McDowell… - Journal of …, 2018 - thejns.org
OBJECTIVE Ventricular shunt (VS) durability has been well studied in the pediatric
population and in patients with normal pressure hydrocephalus; however, further evaluation …

Gravitational shunt valves in hydrocephalus to challenge the sequelae of over-drainage

P Gutowski, L Gölz, S Rot, J Lemcke… - Expert Review of …, 2020 - Taylor & Francis
Introduction In hydrocephalus treatment, ventriculo-peritoneal shunts (VPS) have become
the most relevant therapy for seven decades among other treatment options. Due to the …

Role of psychiatric, cardiovascular, socioeconomic, and demographic risk factors on idiopathic normal pressure hydrocephalus: a retrospective case-control study

A Ghaffari-Rafi, R Gorenflo, H Hu, J Viereck… - Clinical Neurology and …, 2020 - Elsevier
Objectives Currently, predicting and preventing idiopathic normal pressure hydrocephalus
(iNPH) remains challenging, especially for patients without a history of cerebrovascular …