Opportunities and challenges in studying the extracellular vesicle corona

EI Buzas - Nature Cell Biology, 2022 - nature.com
The extracellular vesicle (EV) surface corona is emerging as a crucial mediator of EV
functions. This Comment discusses the roles and biogenesis of the EV corona, as well as …

[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis

MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

HDL in the 21st century: a multifunctional roadmap for future HDL research

A Rohatgi, M Westerterp, A Von Eckardstein… - Circulation, 2021 - Am Heart Assoc
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …

Coronary heart disease risk: low-density lipoprotein and beyond

GE Shaya, TM Leucker, SR Jones, SS Martin… - Trends in cardiovascular …, 2022 - Elsevier
Coronary heart disease (CHD) is the leading cause of morbidity and mortality world-wide
and has been characterized as a chronic immunoinflammatory, fibroproliferative disease …

Spatial exosome analysis using cellulose nanofiber sheets reveals the location heterogeneity of extracellular vesicles

A Yokoi, K Yoshida, H Koga, M Kitagawa… - Nature …, 2023 - nature.com
Extracellular vesicles (EVs), including exosomes, are recognized as promising functional
targets involved in disease mechanisms. However, the intravital heterogeneity of EVs …

Advances in HDL: much more than lipid transporters

S Ben-Aicha, L Badimon, G Vilahur - International Journal of Molecular …, 2020 - mdpi.com
High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …

Effects of curcumin on HDL functionality

S Ganjali, CN Blesso, M Banach, M Pirro… - Pharmacological …, 2017 - Elsevier
Curcumin, a bioactive polyphenol, is a yellow pigment of the Curcuma longa (turmeric) plant.
Curcumin has many pharmacologic effects including antioxidant, anti-carcinogenic, anti …

The exosome encapsulated microRNAs as circulating diagnostic marker for hepatocellular carcinoma with low alpha‐fetoprotein

S Ghosh, S Bhowmik, S Majumdar… - … journal of cancer, 2020 - Wiley Online Library
Diagnosis of hepatocellular carcinoma (HCC) remains challenging to clinicians, particularly
in a patient with low alpha‐fetoprotein. Here, in silico, ex vivo and in vitro data were …

Perspectives of using microRNA-loaded nanocarriers for epigenetic reprogramming of drug resistant colorectal cancers

OA Sukocheva, J Liu, ME Neganova… - Seminars in Cancer …, 2022 - Elsevier
Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …

Cholesterol homeostasis: Researching a dialogue between the brain and peripheral tissues

M Gliozzi, V Musolino, F Bosco, M Scicchitano… - Pharmacological …, 2021 - Elsevier
Cholesterol homeostasis is a highly regulated process in human body because of its several
functions underlying the biology of cell membranes, the synthesis of all steroid hormones …