Mechanisms regulating skeletal muscle growth and atrophy

S Schiaffino, KA Dyar, S Ciciliot, B Blaauw… - The FEBS …, 2013 - Wiley Online Library
Skeletal muscle mass increases during postnatal development through a process of
hypertrophy, ie enlargement of individual muscle fibers, and a similar process may be …

Skeletal muscle hypertrophy and regeneration: interplay between the myogenic regulatory factors (MRFs) and insulin-like growth factors (IGFs) pathways

N Zanou, P Gailly - Cellular and Molecular Life Sciences, 2013 - Springer
Adult skeletal muscle can regenerate in response to muscle damage. This ability is
conferred by the presence of myogenic stem cells called satellite cells. In response to stimuli …

[HTML][HTML] The imprinted H19 lncRNA antagonizes let-7 microRNAs

AN Kallen, XB Zhou, J Xu, C Qiao, J Ma, L Yan, L Lu… - Molecular cell, 2013 - cell.com
Abundantly expressed in fetal tissues and adult muscle, the developmentally regulated H19
long noncoding RNA (lncRNA) has been implicated in human genetic disorders and cancer …

[PDF][PDF] Mechanisms modulating skeletal muscle phenotype

B Blaauw, S Schiaffino, C Reggiani - Compr Physiol, 2013 - researchgate.net
Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Sarcopenia in chronic kidney disease: factors, mechanisms, and therapeutic interventions

H Watanabe, Y Enoki, T Maruyama - Biological and Pharmaceutical …, 2019 - jstage.jst.go.jp
Chronic kidney disease (CKD), a chronic catabolic condition, is characterized by muscle
wasting and decreased muscle endurance. Many insights into the molecular mechanisms of …

Role of IGF-I signaling in muscle bone interactions

DD Bikle, C Tahimic, W Chang, Y Wang, A Philippou… - Bone, 2015 - Elsevier
Skeletal muscle and bone rely on a number of growth factors to undergo development,
modulate growth, and maintain physiological strength. A major player in these actions is …

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

CE Winbanks, JL Chen, H Qian, Y Liu… - Journal of Cell …, 2013 - rupress.org
Although the canonical transforming growth factor β signaling pathway represses skeletal
muscle growth and promotes muscle wasting, a role in muscle for the parallel bone …

[HTML][HTML] Identification of Key Genes and Biological Pathways Associated with Skeletal Muscle Maturation and Hypertrophy in Bos taurus, Ovis aries, and Sus scrofa

F Mohammadinejad, M Mohammadabadi, Z Roudbari… - Animals, 2022 - mdpi.com
Simple Summary One of the traits considered in livestock production is the gain of muscle
mass, which is one of the factors responsible for governing the growth of skeletal muscles …

[HTML][HTML] Endocrine regulation of fetal skeletal muscle growth: impact on future metabolic health

LD Brown - The Journal of endocrinology, 2014 - ncbi.nlm.nih.gov
Establishing sufficient skeletal muscle mass is essential for lifelong metabolic health. The
intrauterine environment is a major determinant of the muscle mass that is present for the life …

[HTML][HTML] S6K1 is required for increasing skeletal muscle force during hypertrophy

M Marabita, M Baraldo, F Solagna, JJM Ceelen… - Cell reports, 2016 - cell.com
Loss of skeletal muscle mass and force aggravates age-related sarcopenia and numerous
pathologies, such as cancer and diabetes. The AKT-mTORC1 pathway plays a major role in …