Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment

HF Escobar-Morreale - Nature Reviews Endocrinology, 2018 - nature.com
Polycystic ovary syndrome (PCOS) is one of the most common endocrine and metabolic
disorders in premenopausal women. Heterogeneous by nature, PCOS is defined by a …

Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications

E Diamanti-Kandarakis, A Dunaif - Endocrine reviews, 2012 - academic.oup.com
Polycystic ovary syndrome (PCOS) is now recognized as an important metabolic as well as
reproductive disorder conferring substantially increased risk for type 2 diabetes. Affected …

[PDF][PDF] ISPAD Clinical Practice Consensus Guidelines 2018: The diagnosis and management of monogenic diabetes in children and adolescents

AT Hattersley, SAW Greeley, M Polak… - 2018 - ore.exeter.ac.uk
Monogenic diabetes results from one or more defects in a single gene. The disease may be
inherited within families as a dominant, recessive or non-Mendelian trait or may present as a …

[HTML][HTML] ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of monogenic diabetes in children and adolescents

SAW Greeley, M Polak, PR Njølstad, F Barbetti… - Pediatric …, 2022 - ncbi.nlm.nih.gov
ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of
monogenic diabetes in children and adolescents - PMC Back to Top Skip to main content NIH …

PI3K/AKT, MAPK and AMPK signalling: protein kinases in glucose homeostasis

SM Schultze, BA Hemmings, M Niessen… - Expert reviews in …, 2012 - cambridge.org
New therapeutic approaches to counter the increasing prevalence of obesity and type 2
diabetes mellitus are in high demand. Deregulation of the phosphoinositide-3-kinase …

Congenital generalized lipodystrophies—new insights into metabolic dysfunction

N Patni, A Garg - Nature Reviews Endocrinology, 2015 - nature.com
Congenital generalized lipodystrophy (CGL) is a heterogeneous autosomal recessive
disorder characterized by a near complete lack of adipose tissue from birth and, later in life …

Genetic syndromes of severe insulin resistance

RK Semple, DB Savage, EK Cochran… - Endocrine …, 2011 - academic.oup.com
Insulin resistance is among the most prevalent endocrine derangements in the world, and it
is closely associated with major diseases of global reach including diabetes mellitus …

Abdominal adiposity and the polycystic ovary syndrome

HF Escobar-Morreale, JL San Millán - Trends in Endocrinology & …, 2007 - cell.com
Abdominal adiposity, overweightness and obesity are frequently present in patients with
polycystic ovary syndrome (PCOS). A large body of evidence suggests that abdominal …

An update of genetic basis of PCOS pathogenesis

RP Crespo, TASS Bachega, BB Mendonça… - … of endocrinology and …, 2018 - SciELO Brasil
Polycystic ovary syndrome (PCOS) is a common and complex endocrine disorder that
affects 5-20% of reproductive age women. PCOS clinical symptoms include hirsutism …

[PDF][PDF] The diagnosis and management of monogenic diabetes in children and adolescents.

O Rubio‐Cabezas, AT Hattersley, PR Njølstad… - Pediatric diabetes, 2014 - bnsde.org
Monogenic diabetes results from one or more defects in a single gene. The disease may be
inherited within families as a dominant, recessive, or non-Mendelian trait or may present as …