Synthetic mimics of biotin/(strept) avidin
Biotin/(strept) avidin self-assembly is a powerful platform for nanoscale fabrication and
capture with many different applications in science, medicine, and nanotechnology …
capture with many different applications in science, medicine, and nanotechnology …
Molecular conjugation using non-covalent click chemistry
CL Schreiber, BD Smith - Nature Reviews Chemistry, 2019 - nature.com
Molecular conjugation refers to methods used in biomedicine, advanced materials and
nanotechnology to link two partners—from small molecules to large and sometimes …
nanotechnology to link two partners—from small molecules to large and sometimes …
Synthetic host-guest pairs as novel bioorthogonal tools for pre-targeting
YL Ma, S Yan, XJ Xu, H Cao, R Wang - Chinese Chemical Letters, 2024 - Elsevier
Due to its simplicity, high efficiency, and chemo-selectivity, bioorthogonal chemistry has
shown a great application potential in pre-targeting. Currently, four bioorthogonal pairs as …
shown a great application potential in pre-targeting. Currently, four bioorthogonal pairs as …
Structural transformation in metal–organic frameworks for reversible binding of oxygen
Polycyclic aromatic derivatives can trap 1O2 to form endoperoxides (EPOs) for O2 storage
and as sources of reactive oxygen species. However, these materials suffer from structural …
and as sources of reactive oxygen species. However, these materials suffer from structural …
Charge-assisted hydrogen bonding in a bicyclic amide cage: an effective approach to anion recognition and catalysis in water
Hydrogen bonding is prevalent in biological systems, dictating a myriad of life-sustaining
functions in aqueous environments. Leveraging hydrogen bonding for molecular recognition …
functions in aqueous environments. Leveraging hydrogen bonding for molecular recognition …
Steric protection of near-infrared fluorescent dyes for enhanced bioimaging
SSR Kommidi, KM Atkinson, BD Smith - Journal of Materials Chemistry …, 2024 - pubs.rsc.org
Near-fluorescent (NIR) dyes that absorb and emit light in the wavelength range of 650–1700
nm are well-suited for bioimaging due to the improved image contrast and increased …
nm are well-suited for bioimaging due to the improved image contrast and increased …
Guest back-folding: a molecular design strategy that produces a deep-red fluorescent host/guest pair with picomolar affinity in water
One of the major goals of modern supramolecular chemistry, with important practical
relevance in many technical fields, is the development of synthetic host/guest partners with …
relevance in many technical fields, is the development of synthetic host/guest partners with …
High-affinity single and double helical pseudofoldaxanes with cationic guests
Two aromatic oligoamides, the 8-residue H8 and 16-residue H16, that adopt stable, cavity-
containing helical conformations were examined for their complexation of a rodlike …
containing helical conformations were examined for their complexation of a rodlike …
Supramolecular mitigation of the cyanine limit problem
Currently, there is a substantial research effort to develop near-infrared fluorescent
polymethine cyanine dyes for biological imaging and sensing. In water, cyanine dyes with …
polymethine cyanine dyes for biological imaging and sensing. In water, cyanine dyes with …
Fluorescent neuraminidase assay based on supramolecular dye capture after enzymatic cleavage
W Liu, CFA Gómez-Durán… - Journal of the American …, 2017 - ACS Publications
A conceptually new type of enzymatic cleavage assay is reported that utilizes in situ
supramolecular capture of the fluorescent product. A squaraine-derived substrate with large …
supramolecular capture of the fluorescent product. A squaraine-derived substrate with large …