[HTML][HTML] HIV infection and AIDS in sub-Saharan Africa: current status, challenges and opportunities

ABM Kharsany, QA Karim - The open AIDS journal, 2016 - ncbi.nlm.nih.gov
Global trends in HIV infection demonstrate an overall increase in HIV prevalence and
substantial declines in AIDS related deaths largely attributable to the survival benefits of …

[HTML][HTML] Human papillomavirus in the setting of immunodeficiency: Pathogenesis and the emergence of next-generation therapies to reduce the high associated …

RV Hewavisenti, J Arena, CL Ahlenstiel… - Frontiers in …, 2023 - frontiersin.org
Human papillomavirus (HPV), a common sexually transmitted virus infecting mucosal or
cutaneous stratified epithelia, is implicated in the rising of associated cancers worldwide …

[HTML][HTML] Lactobacillus-deficient cervicovaginal bacterial communities are associated with increased HIV acquisition in young South African women

C Gosmann, SA Handley, M Farcasanu, G Abu-Ali… - Immunity, 2017 - cell.com
Elevated inflammation in the female genital tract is associated with increased HIV risk.
Cervicovaginal bacteria modulate genital inflammation; however, their role in HIV …

Vaginal bacteria modify HIV tenofovir microbicide efficacy in African women

NR Klatt, R Cheu, K Birse, AS Zevin, M Perner… - Science, 2017 - science.org
Antiretroviral-based strategies for HIV prevention have shown inconsistent results in women.
We investigated whether vaginal microbiota modulated tenofovir gel microbicide efficacy in …

[HTML][HTML] Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

EH Byrne, KE Doherty, BA Bowman, HS Yamamoto… - Immunity, 2015 - cell.com
Colonization by Lactobacillus in the female genital tract is thought to be critical for
maintaining genital health. However, little is known about how genital microbiota influence …

[HTML][HTML] Bacterial vaginosis: drivers of recurrence and challenges and opportunities in partner treatment

LA Vodstrcil, CA Muzny, EL Plummer, JD Sobel… - BMC medicine, 2021 - Springer
Bacterial vaginosis (BV) is the most common vaginal dysbiosis to affect women globally, yet
an unacceptably high proportion of women experience BV recurrence within 6 months of …

Sexually transmitted infections and HIV in the era of antiretroviral treatment and prevention: the biologic basis for epidemiologic synergy

MS Cohen, OD Council, JS Chen - Journal of the International …, 2019 - Wiley Online Library
Introduction HIV is a unique sexually transmitted infection (STI) that is greatly affected by
other concomitant “classical” bacterial and viral STI s that cause genital ulcers and/or …

Increased risk of HIV acquisition among women throughout pregnancy and during the postpartum period: a prospective per-coital-act analysis among women with HIV …

KA Thomson, J Hughes, JM Baeten… - The Journal of …, 2018 - academic.oup.com
Background Understanding the absolute and relative risk of human immunodeficiency virus
type 1 (HIV) acquisition during pregnancy and the postpartum period can inform HIV …

[HTML][HTML] Sex differences in HIV infection

EP Scully - Current HIV/AIDS Reports, 2018 - Springer
Abstract Purpose of Review This review will outline the multilevel effects of biological sex on
HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential …

[HTML][HTML] Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and …

KB Arnold, A Burgener, K Birse, L Romas… - Mucosal …, 2016 - Elsevier
Elevated inflammatory cytokines (EMCs) at mucosal surfaces have been associated with
HIV susceptibility, but the underlying mechanisms remain unclear. We characterized the …