Brain metastases (BM) are the most commonly diagnosed type of central nervous system
tumor in the United States. Estimates of the frequency of BM vary significantly, as there is no …

METHODS Details of the systematic literature review are provided in the full text of this
guideline (https://www. cns. org/guidelines/guidelines-treatment-adults-metastatic-brain …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

BACKGROUND The validity of the KRAS mutation as a predictor of recurrence‐free survival
(RFS) or overall survival (OS) is unclear. The current study investigated whether the …

Background Brain metastases (BM) from colorectal cancer (CRC) are a rare event. However,
the implications for affected patients are severe, and the incidence has been reported to be …

Background Colorectal cancer is the third most common cancer in Australia. The median
overall survival for metastatic colorectal cancer is nearly 2 years. However, there may be …

Somatic mutation status in metastatic colorectal cancer (CRC), and namely mutational
activation of the Kirsten rat sarcoma viral oncogene homolog (KRAS) oncogene, is …

Background Brain metastases (BM) from the gastrointestinal tract (GIT) cancers are relatively
rare. Despite those advances in diagnostic and treatment options, life expectancy and …

The aim of the study was to investigate the predictive impact of extracranial metastatic
patterns on course of disease and survival in patients with colorectal cancer (CRC) and …

Background For brain metastases from non-specific primary tumors, the most frequently
used and validated clinical prognostic assessment tool is Karnofsky performance status …